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©The Author(s) 2025.
World J Gastrointest Surg. Jun 27, 2025; 17(6): 105073
Published online Jun 27, 2025. doi: 10.4240/wjgs.v17.i6.105073
Published online Jun 27, 2025. doi: 10.4240/wjgs.v17.i6.105073
Table 1 Patients characteristics and lesion profiles (n = 113)
Characteristics | N = 113 |
Age (years) | 57.3 ± 11.9 |
BMI (kg/m2) | 21.2 ± 3.2 |
Gender, n (%) | |
Male/female | 71 (62.8)/42 (37.2) |
Lesion thickness (cm) | 1.5 ± 0.6 |
Lesion length (cm) | 5.2 ± 2.3 |
Presence of angle sign, n (%) | |
Yes/no | 89 (78.7)/24 (21.3) |
Presence of ulcer, n (%) | |
Yes/no | 63 (55.7)/50 (44.3) |
Lesion location, n (%) | |
Gastric antrum | 53 (46.9) |
Gastric fundus | 12 (10.6) |
Gastric body | 33 (29.3) |
Gastric fundus + body | 11 (9.7) |
Gastric angle | 4 (3.5) |
Clinical feature, n (%) | |
Epigastrium discomfort or dull pain | 36 (31.9) |
Abdominal pain with black stool | 18 (15.9) |
Abdominal pain with belching | 22 (19.5) |
Abdominal distension with anorexia | 17 (15.0) |
Abdominal pain with vomiting | 15 (13.3) |
Dysphagia | 5 (4.4) |
CEA, n (%) | |
< 5 μg/L/≥ 5 μg/L | 79 (69.9)/34 (30.1) |
CA19-9, n (%) | |
< 37 kU/L/≥ 37 kU/L | 85 (75.2)/28 (24.8) |
Pathological type, n (%) | |
Adenocarcinoma | 113 (100.0) |
Histologic type, n (%) | |
Poor differentiated | 71 (62.8) |
Moderate differentiated | 37 (32.8) |
Well differentiated | 5 (4.4) |
Lauren type, n (%) | |
Diffuse type | 70 (61.9) |
Hybrid type | 15 (13.3) |
Intestinal type | 28 (24.8) |
Table 2 Univariate analysis of influence factors between pathological T1-T2 staging and T3-T4 staging
Variable | T3-T4 staging (n = 92) | T1-T2 staging (n = 21) | t/χ2 | P value |
Age (years) | 58.4 ± 12.2 | 57.7 ± 10.9 | -0.250 | 0.803 |
BMI (kg/m2) | 21.4 ± 3.2 | 20.1 ± 2.9 | -1.862 | 0.065 |
Gender | ||||
Male/female | 61/31 | 10/11 | 2.556 | 0.110 |
Lesion thickness (cm) | 1.6 ± 0.6 | 1.0 ± 0.4 | -4.022 | < 0.001 |
Lesion length (cm) | 5.7 ± 2.2 | 2.9 ± 1.0 | -5.596 | < 0.001 |
Presence of angle sign | ||||
Yes/no | 85/7 | 4/17 | 50.684 | < 0.001 |
Presence of ulcer | ||||
Yes/no | 52/40 | 11/10 | 0.119 | 0.730 |
Lesion location | ||||
Gastric antrum | 44 | 9 | 7.740 | 0.102 |
Gastric fundus | 9 | 3 | ||
Gastric body | 30 | 3 | ||
Gastric fundus + body | 6 | 5 | ||
Gastric angle | 3 | 1 | ||
CEA | 58/34 | 21/0 | < 0.001 | |
< 5 μg/L/≥ 5 μg/L | ||||
CA19-9 | 67/25 | 18/3 | 0.911 | 0.034 |
< 37 kU/L/≥ 37 kU/L | ||||
Clinical feature | ||||
Epigastrium discomfort or dull pain | 29 | 7 | 0.758 | |
Abdominal pain with black stool | 15 | 3 | ||
Abdominal pain with belching | 17 | 5 | ||
Abdominal distension with anorexia | 15 | 2 | ||
Abdominal pain with vomiting | 13 | 2 | ||
Dysphagia | 3 | 2 | ||
Histologic type | ||||
Poor differentiated | 60 | 11 | 2.190 | 0.335 |
Moderate differentiated | 29 | 8 | ||
Well differentiated | 3 | 2 | ||
Lauren type | ||||
Diffuse type | 60 | 10 | 2.579 | 0.275 |
Hybrid type | 12 | 3 | ||
Intestinal type | 20 | 8 |
Table 3 Multivariate analysis of influence factors between pathological T1-T2 staging and T3-T4 staging
B | SE | P value | OR | 95%CI | |
Lesion thickness (cm) | - | - | 0.933 | - | - |
Lesion length (cm) | 0.864 | 0.315 | 0.006 | 2.373 | 1.281-4.396 |
Angle sign (yes/no) | 3.437 | 0.992 | < 0.001 | 31.083 | 4.449-217.164 |
CA19-9 (< 37 kU/L/≥ 37 kU/L) | - | - | 0.308 | - | - |
CEA (< 5 μg/L/≥ 5 μg/L) | - | - | 0.997 | - | - |
- Citation: Zhong MY, Jian GL, Ye JY, Liu QX, Huang WJ, Zhen CJ. Clinical characteristics and transabdominal ultrasound features that associated with T3-T4 staging in gastric cancer: A retrospective study. World J Gastrointest Surg 2025; 17(6): 105073
- URL: https://www.wjgnet.com/1948-9366/full/v17/i6/105073.htm
- DOI: https://dx.doi.org/10.4240/wjgs.v17.i6.105073