Observational Study
Copyright ©The Author(s) 2021.
World J Gastrointest Surg. Feb 27, 2021; 13(2): 176-186
Published online Feb 27, 2021. doi: 10.4240/wjgs.v13.i2.176
Table 1 Characteristics of T1b gallbladder cancer patients who underwent cholecystectomy alone or cholecystectomy combined with regional lymphadenectomy
Characteristic
Ch, n = 44
Ch + RL, n = 77
P value
Age, mean ± SD in yr62.8 ± 11.361.4 ± 9.40.48
Female34 (77.3)57 (74.3)0.69
Admitted to high-volume centers122 (50.0)46 (59.7)0.30
Nodal metastasis3
Negative, N00 (0)55 (71.4)
Positive, N+1 (2.3)7 (9.1)
Undetermined, Nx43 (97.7)15 (19.5)
No. of examined nodes, median (range)0 (0-1)3 (0-14)3
Malignancy diagnosed after primary surgery25 (56.8)15 (19.5)< 0.001b
Hepatectomy2 (4.5)254 (70.1)< 0.001b
Liver wedge resection2 (4.5)51 (66.2)
Segment IVb + V resection0 (0)3 (3.9)
Bile duct resection1 (2.3)5 (6.5)0.41
Negative resection margin40 (90.9)73 (94.8)0.46
Poor histological grade4 (9.1)15 (19.5)0.19
Microscopic vascular invasion0 (0)3 (3.9)0.55
Perineural invasion0 (0)1 (1.3)1.00
Table 2 Association between surgery type and overall survival in T1b gallbladder cancer patients
Variable
Model 1
Model 2
Model 3
Ch + RL vs Ch0.50 (0.26-0.97)a0.47 (0.24-0.92)0.51 (0.26-0.99)a
Age > 60-years-old1.73 (0.82-3.64)1.91 (0.89-4.10)
Female sex0.68 (0.33-1.39)0.60 (0.29-1.26)
High hospital volume0.97 (0.50-1.89)0.99 (0.50-1.95)
Negative margin0.31 (0.11-0.83)b

  • Citation: Ren T, Li YS, Dang XY, Li Y, Shao ZY, Bao RF, Shu YJ, Wang XA, Wu WG, Wu XS, Li ML, Cao H, Wang KH, Cai HY, Jin C, Jin HH, Yang B, Jiang XQ, Gu JF, Cui YF, Zhang ZY, Zhu CF, Sun B, Dai CL, Zheng LH, Cao JY, Fei ZW, Liu CJ, Li B, Liu J, Qian YB, Wang Y, Hua YW, Zhang X, Liu C, Lau WY, Liu YB. Prognostic significance of regional lymphadenectomy in T1b gallbladder cancer: Results from 24 hospitals in China. World J Gastrointest Surg 2021; 13(2): 176-186
  • URL: https://www.wjgnet.com/1948-9366/full/v13/i2/176.htm
  • DOI: https://dx.doi.org/10.4240/wjgs.v13.i2.176