Hyponatremia is associated with more severe biliary disease

doi:10.4240/wjgs.v12.i2.45

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Feb 27, 2020; 12(2): 45-54
Published online Feb 27, 2020. doi: 10.4240/wjgs.v12.i2.45

Table 1 Bivariate and multivariate analysis of sodium level and clinical factors

		n (%)	Na (mEq/L)	Bivariate (P value)	Multivariate (P value)
Age¹	< 50 yr	150 (16)	138.3	0.0001	0.821
	50-69 yr	487 (53)	136.6
	≥ 70 yr	283 (31)	135.8
Glucose¹	Normal (< 115 mg/dL)	392 (44)	137.6	0.0001	0.127
Glucose¹	Elevated (≥ 115 mg/dL)	501 (56)	135.7	0.0001	0.127
Illness severity	No infectious manifestations	403 (44)	138.7	0.0001	0.0001
	SIRS	196 (21)	136.7
	Severe	154 (17)	134.7
	Sepsis/MODS	167 (18)	133.2
Bacterial location	None/sterile	396 (45)	138.3	0.0001	0.023
	Gallstone only	60 (7)	137.2
	Bile	338 (38)	135.4
	Blood	85 (10)	133.1
Gangrenous changes	None	732 (80)	137.3	0.0001	0.002
Gangrenous changes	Gangrene	188 (20)	133.8	0.0001	0.002
Charlson Co-Morbidity index¹	0-2	518 (57)	137.4	0.0001	0.001
	3-4	261 (29)	136.2
	5 or more	140 (14)	134.6

¹Analyzed as a continuous variable. MODS: Multisystem organ dysfunction syndrome; SIRS: Systemic inflammatory response syndrome; Gangrenous changes: Gangrenous cholecystitis, gallbladder perforation, abscess, necrotizing pancreatitis.

Citation: Zobel MJ, Stewart L. Hyponatremia is associated with more severe biliary disease. World J Gastrointest Surg 2020; 12(2): 45-54
URL: https://www.wjgnet.com/1948-9366/full/v12/i2/45.htm
DOI: https://dx.doi.org/10.4240/wjgs.v12.i2.45