Colorectal cancer risk in hamartomatous polyposis syndromes

Figure 1 Histological features of a Peutz-Jeghers polyp. Note that they are typically multilobulated with a papillary surface and branching bands of smooth muscle covered by hyperplastic glandular mucosa.

Figure 2 A Juvenile Polyp exhibiting a normal epithelium with a dense stroma, an inflammatory infiltrate and a smooth surface with dilated, mucus-filled cystic glands in the lamina propria.

Figure 3 Mucocutaneous pigmentation in Peutz-Jeghers Syndrome.

Figure 4 Prolapsed polyp through the anus in a patient with Juvenile Polyposis.

Figure 5 Feet queratosis (A), multiple facial triquilemomas (B) and oral mucosa papilomatosis (C) in a patients with Cowden’s Syndrome.