CDX2 as a marker for intestinal differentiation: Its utility and limitations

Figure 1 CDX2 expression. A: CDX2 expression in metastatic ileal carcinoid to the liver. Please note the presence of moderate nuclear staining; B: CDX2 expression is also seen in appendiceal goblet carcinoid (Immunohistochemistry × 400); C: CDX2 expression in cytology specimens of metastatic colonic carcinoma to the lung, supporting their colorectal origin. (Immunohistochemistry × 250); D: CDX2 expression is seen in the majority of endocervical adenocarcinomas of intestinal type (Immunohistochemistry × 400); E: CDX2 expression in endometrioid carcinoma (Immunohistochemistry × 400); F: CDX2 expression in sinonasal adenocarcinoma of intestinal type (Immunohistochemistry × 400).