Can molecular biomarkers replace a clinical risk score for resectable colorectal liver metastasis?

Table 1 The clinical risk score (as suggested by Fong et al[8])

Score	0	1	Predicted 5-yr survival
Nodal status of primary tumor (pN0 vs pN+)	-	+
Disease-free interval1	> 12 mo	< 12 mo
Number of tumors	≤ 1	> 1
Pre-operative CEA level	≤ 200 ng/mL	> 200 ng/mL
Size of largest tumor	≤ 5 cm	> 5 cm
Score
0			60%
1			44%
2			40%
3			20%
4			25%
5			14%

¹From primary tumor to discovery of liver metastasis. CEA: Carcino-embryonic antigen.