Copyright ©2010 Baishideng.
World J Gastrointest Oncol. Apr 15, 2010; 2(4): 192-196
Published online Apr 15, 2010. doi: 10.4251/wjgo.v2.i4.192
Table 1 Classification and staging of appendiceal NETs according to the TNM system
Τ3Any ΝΜ0
IVAny ΤAny ΝΜ1
Table 2 Recommended surgical strategies for appendiceal NETs based on specific clinical and histological characteristics
IndicationsType of operation
Tumor size < 1 cmAppendicectomy
Tumor size 1-2 cmAppendicectomy + Regular F/Up for 5 years
Tumor size > 2 cmRight hemicolectomy
Location of the tumor at the base of the appendixRight hemicolectomy
Infiltration of the cecumRight hemicolectomy
Positive surgical resection marginsRight hemicolectomy
Appendiceal mesentery invasionRight hemicolectomy
Metastatically infiltrated mesoappendiceal lymph nodeRight hemicolectomy
Presence of undifferentiated or low differentiated cellsRight hemicolectomy
Presence of goblet cells
Goblet cell carcinoma in malesRight hemicolectomy
Goblet cell carcinoma in females (regardless of age)Right hemicolectomy + Bilateral salpingo-oophorectomy
Peritoneal dissemination from goblet cell carcinomaCytoreductive surgery + Adjuvant intraperitoneal chemotherapy