Resveratrol suppresses ulcerative colitis and colitis-associated colorectal cancer via modulating the miR-31-5p/SATB2 axis

Table 1 Quantitative reverse transcription polymerase chain reaction primer sequences

Target gene	Primer (5'-3')
hsa-miR-31-5p	5'-AGGCAAGAUGCUGGCAUAGCU-3'
hsa-U6	5'-TATTGCTTAAGAATACGCGGTAGAAA-3'
mmu-miR-31	5'-GCAAGATGCTGGCATAGCTGAA-3'
mmu-U6	5'-CTCGCTTCGGCAGCACATATACTACGCTTCACGAATTTGCGTGTC-3'
SATB2	F: 5'-CCTCCTCCGACTGAAGACAG-3'
	R: 5'-TGGTCTGGGTACAGGCCTAC-3'
PPP2R2A	F: 5'-TGGTTACCCCAGAAAAATGC-3'
	R: 5'-TGGCCTCAACCATTAGATCC-3'
GAPDH	F: 5'-GGACTTCGAGCAAGAGATGG-3'
	R: 5'-AGCACTGTGTTGGCGTACAG-3'

hsa: Human; mmu: Mouse; F: Forward; R: Reverse.

Table 2 Effects of resveratrol on tumor incidence, multiplicity, and size in the azoxymethane/dextran sulfate sodium-induced colitis-associated colorectal cancer model

Group	n	Tumor incidence (%)	Tumor multiplicity (mean)	Mean tumor size (mm)
Control	4	0	0	0
AOM	4	0	0	0
AOM/DSS	14	73.3	2.47	5.72796
AOM/DSS + Res	11	16.7	0.25	4.1664
Res	5	0	0	0

AOM: Azoxymethane; DSS: Dextran sulfate sodium; Res: Resveratrol.