Review
Copyright ©The Author(s) 2020.
World J Gastrointest Oncol. Aug 15, 2020; 12(8): 833-849
Published online Aug 15, 2020. doi: 10.4251/wjgo.v12.i8.833
Table 1 World Health Organization classification of exocrine malignant epithelial tumors 5th edition
HistotypeSubtypeFrequency, %
Ductal adenocarcinomaNOS85%
Carcinoma undifferentiated1%-7%
Adenosquamous carcinoma1%-4%
Undifferentiated carcinoma with osteoclast-like giant cell< 1%
Colloid carcinoma1%-3%
Poorly cohesive carcinomaExtremely rare
Signet-ring cell carcinomaExtremely rare
Medullary carcinoma NOSExtremely rare
Hepatoid carcinomaExtremely rare
Large cell with rhabdoid phenotypeExtremely rare
Acinar cell carcinomaNOS< 2%
Acinar cell cystadenocarcinomaExtremely rare
Mixed acinar-neuroendocrine carcinomaExtremely rare
Mixed acinar-endocrine-ductal carcinomaExtremely rare
Mixed acinar -ductal carcinomaExtremely rare
PancreatoblastomaExtremely rare
Solid pseudopapillary neoplasmNOS3%
With high-grade carcinomaExtremely rare