Value of macrobiopsies and transanal endoscopic microsurgery in the histological work-up of rectal neoplasms: A retrospective study

Table 1 Flexible endoscopy: Sensitivity for invasive growth; correlation with the number of biopsies

Number of biopsies		≤ 2	3	4	5	6	7	8	≥ 9
Marshall (1993)	Sens			68.3		78.3		78.3	78.3
	n = 701			70		70		70	70
Colleypriest (2009)	Sens	80%	86%	86%	88%	98%	100%	98%	100%
	n = 217	Not specified
Dabos (2011)	Sens		50%	72%	70%	76%	88%	91%	100%
	n = 149	Not specified
Current study	Sens	40%	30%	76%	75%	83%	50%	91%	72%
	n = 113	7	12	21	17	14	16	13	13

¹Authors studied the value of reviewing 2, 4 and 6 additional biopsies, taken in every patient.