Risk factors and classifications of hilar cholangiocarcinoma

Table 3 Consensus classification (European Hepato-Pancreato-Biliary Association)

Label	Side location	Description
Bile duct (B)
B1		Common bile duct
B2		Hepatic duct confluence
B3	R	Right hepatic duct
B3	L	Left hepatic duct
B4		Right and left hepatic duct
Tumor size (T)
T1		< 1 cm
T2		1-3 cm
T3		≥ 3 cm
Tumor form (F)
Sclerosing		Sclerosing (or periductal)
Mass		Mass-forming (or nodular)
Mixed		Sclerosing and mass-forming
Polypoid		Polypoid (or intraductal)
Involvement (> 180°) of the portal vein (PV)
PV0		No portal involvement
PV1		Main portal vein
PV2		Portal vein bifurcation
PV3	R	Right portal vein
PV3	L	Left portal vein
PV4		Right and left portal veins
Involvement (> 180°) of the hepatic artery (HA)
HA0		No portal involvement
HA1		Proper hepatic artery
HA2		Hepatic artery bifurcation
HA3	R	Right hepatic artery
HA3	L	Left hepatic artery
HA4		Right and left hepatic artery
Liver remnant volume (V)
V0		No information on the volume needed (liver resection not foreseen)
V%	Indicate segments	Percentage of the total volume of a putative rem-nant liver after resection
Underlying liver disease (D)		Fibrosis
		Nonalcoholic steatohepatitis
		Primary sclerosing cholangitis
Lymph nodes (N)
N0		No lymph node involvement
N1		Hilar and/or hepatic artery lymph node involvement
N2		Periaortic lymph node involvement
Metastases (M)
M0		No distant metastases
M1		Distant metastases (including liver and peritoneal metastases)

R: Right; L: Left.