Comprehensive analysis of the potential pathogenesis of COVID-19 infection and liver cancer

Figure 8 Construction and analysis of the regulatory network of transcription factor genes and hub genes. A: Transcription factor (TF)-hub gene regulatory network, highlighted red nodes indicate hub genes and yellow nodes indicate TF genes; B: Analysis of differential expression of TF gene e2f transcription factor 1 in disease; C: Differential analysis of TF gene sp1 transcription factor expression in disease. ^aP < 0.05, ^cP < 0.001 E2F1: e2f transcription factor 1; SP1: sp1 transcription factor; AURKB: Aurora kinase B; CCNB2: Cyclin B2; CHEK1: Checkpoint kinase 1.