Selenium as a chemopreventive agent in experimentally induced colon carcinogenesis

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Oct 15, 2009 (publication date) through Sep 19, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Oct 15, 2009; 1(1): 74-81
Published online Oct 15, 2009. doi: 10.4251/wjgo.v1.i1.74

Table 2 Chemopreventive efficacy of selenium on the tumor incidence, tumor multiplicity and tumor size of DMH-induced rat colonic tumors

Groups	Colon tumor incidence (percentage of tumor bearing rats)	Colon tumor multiplicity (mean tumor/animal)	Tumor size (cm)
Normal control	0	0	-
DMH	100%	2.6	0.911 ± 0.196
Selenium	0	0	-
DMH + selenium	60%	1.1	0.609 ± 0.250^b

^bP < 0.001 by one way-ANOVA followed by LSD test when values of IV animals were compared with Group II animals. Values are expressed as mean + SD.

Citation: Ghadi FE, Ghara AR, Bhattacharyya S, Dhawan DK. Selenium as a chemopreventive agent in experimentally induced colon carcinogenesis. World J Gastrointest Oncol 2009; 1(1): 74-81
URL: https://www.wjgnet.com/1948-5204/full/v1/i1/74.htm
DOI: https://dx.doi.org/10.4251/wjgo.v1.i1.74