Case Report
Copyright ©The Author(s) 2015.
World J Gastrointest Oncol. Aug 15, 2015; 7(8): 118-122
Published online Aug 15, 2015. doi: 10.4251/wjgo.v7.i8.118
Figure 1
Figure 1 Results of pre-operative examinations. A: Endoscopic findings showing a submucosal lesion of 15 mm in diameter on the anterior wall of the upper gastric body near the esophago-gastric junction. The surface was covered with normal gastric mucosa; B: Barium gastrography showed a smooth elevated lesion of 2 cm in diameter on the anterior wall of the upper gastric body near the esophago-gastric junction; C: Computed tomography revealed a 15-mm submucosal low density area with calcification in the anterior wall of the upper gastric body. No lymph node or distant metastasis was detected; D: Endoscopic ultrasound showed an 11.2 mm × 13.5 mm submucosal tumor derived from the third layer of the gastric wall as a heterogeneous lesion with a mixture of a high echoic lesion, low echoic lesion, and calcification.
Figure 2
Figure 2 Results of histopathological examinations. A: The resected specimen had negative lateral and vertical margins with normal mucosa; B: A pathological examination confirmed that the tumor was intrasubmucosal (the depth of invasion into the submucosal layer was 5000 μm), measured 20 mm × 11 mm × 6 mm, and was a well differentiated adenocarcinoma; C: Dilated gastric glands were found in the submucosal layer. There was no lymphovascular invasion; D: An immunostaining method showed MUC5AC (+) and MUC6 (+), indicating differentiation into the pyloric glands.

  • Citation: Imamura T, Komatsu S, Ichikawa D, Kobayashi H, Miyamae M, Hirajima S, Kawaguchi T, Kubota T, Kosuga T, Okamoto K, Konishi H, Shiozaki A, Fujiwara H, Ogiso K, Yagi N, Yanagisawa A, Ando T, Otsuji E. Gastric carcinoma originating from the heterotopic submucosal gastric gland treated by laparoscopy and endoscopy cooperative surgery. World J Gastrointest Oncol 2015; 7(8): 118-122
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