Exploring the role of the systemic immune-inflammation index in colorectal cancer: A study on screening and prognostic assessment

Figure 1 Comparison of inflammatory and immune parameters between the colorectal cancer group and the colorectal adenoma group. A-H: Box-and-whisker plots comparing eight parameters between colorectal cancer (n = 141, blue) and adenoma (n = 191, green) groups: Platelet count (A), neutrophil-to-lymphocyte ratio (B), neutrophil (C), systemic immune-inflammation index (D), lymphocyte (E), albumin (F), platelet-to-lymphocyte ratio (G), C-reactive protein (H). Data are presented as median with IQR. ^aP < 0.01 (Mann-Whitney U test). NLR: Neutrophil-to-lymphocyte ratio; SII: Systemic immune-inflammation index; PLR: Platelet-to-lymphocyte ratio; CRP: C-reactive protein.

Figure 2 Receiver operating characteristic curves of systemic immune inflammation index for distinguishing colorectal adenoma from colorectal cancer. A: Receiver operating characteristic curves for C-reactive protein, platelet-to-lymphocyte ratio, neutrophil-to-lymphocyte ratio, and systemic immune-inflammation index in distinguishing colorectal cancer from adenoma; B: Area under the curve values and cut-offs are shown in Table 4. CRP: C-reactive protein; PLR: Platelet-to-lymphocyte ratio; NLR: Neutrophil-to-lymphocyte ratio; SII: Systemic immune-inflammation index.