Marked elevation of alpha fetoprotein caused by hepatoid adenocarcinoma of stomach: A case report

Figure 1 Portal venous phase of computed tomography liver quad phase. A: Portal vein thrombosis with splenic vein thrombosis; B: Nodularity on the liver surface with segment II liver lesion.

Figure 2 Magnetic resonance imaging liver. A: Portal vein thrombosis; B: Gastric mass. There is no evidence of hepatocellular carcinoma.

Figure 3 Endoscopic photos of the gastric tumour detected during gastroscopy.

Figure 4 Histopathological findings. Hematoxylin and eosin staining of gastric biopsy demonstrating hepatoid adenocarcinoma of the gastrointestinal tract. Tumour shows pleomorphic nests and trabecular pattern mimicking that of hepatocellular carcinoma. A: 200 × magnification; B: 400 × magnification.

Figure 5 Immunohistochemistry findings. All images shown at 200 × magnification. A: Cytokeratin AE1AE3 stain strong positive; B: Caudal type homeobox 2 stain positive; C: Hepatocyte paraffin 1 stain positive; D: Alpha-fetoprotein stain positive.