• CT imaging features
• Diagnostic accuracy
• Solid pseudopapillary neoplasms of the pancreas

• Humans
• Male
• Female
• Pancreatic Neoplasms/diagnostic imaging
• Pancreatic Neoplasms/pathology
• Pancreatic Neoplasms/surgery
• Tomography, X-Ray Computed/methods
• Retrospective Studies
• Adult
• Middle Aged
• Young Adult
• Adolescent
• Prognosis
• Aged
• Follow-Up Studies
• Carcinoma, Papillary/diagnostic imaging
• Carcinoma, Papillary/pathology
• Carcinoma, Papillary/surgery
• Carcinoma, Papillary/diagnosis

• No. 4246ZP112 the Chongqing Talent Plan
• No. 4246ZP112 the Chongqing Talent Plan
• No. 4246ZP112 the Chongqing Talent Plan
• No. 4246ZP112 the Chongqing Talent Plan
• No. 4246ZP112 the Chongqing Talent Plan
• No. 4246ZP112 the Chongqing Talent Plan
• No. 4246ZP112 the Chongqing Talent Plan
• No. 4246ZP112 the Chongqing Talent Plan
• No. 4246ZP112 the Chongqing Talent Plan
• No. 4246ZP112 the Chongqing Talent Plan

• Pancreas
• pancreatic resection
• pancreatic tumor
• solid pseudopapillary tumor

• Frantz's tumor
• Pancreas
• Pancreatic neoplasms
• Pancreatic surgery
• Solid pseudopapillary tumor

• Adult
• Female
• Humans
• Male
• Neoplasm Recurrence, Local/epidemiology
• Neoplasm Recurrence, Local/prevention & control
• Pancreatectomy/adverse effects
• Pancreatic Neoplasms/surgery
• Pancreatic Neoplasms/mortality
• Pancreatic Neoplasms/pathology
• Treatment Outcome

• diagnosis
• hepatic metastases
• prognosis
• solid pseudopapillary neoplasm
• treatment

• Case report
• Frantz tumor
• Neoplasms
• Pancreas
• Pancreatectomy
• Pseudopapillary

• immunohistochemistry
• pancreaticoduodenectomy
• solid pseudopapillary epithelial neoplasm of the pancreas
• splenic vein thrombosis
• telepathology

• Adult
• Humans
• Child
• Pancreatic Neoplasms/surgery
• Pancreatic Neoplasms/pathology
• Pancreas/surgery
• Pancreatectomy
• Pancreaticoduodenectomy
• Carcinoma, Papillary/surgery
• Carcinoma, Papillary/pathology

• Duodenum-preserving pancreatic head resection
• Enucleation
• Laparoscopy
• Pancreatectomy

• 2021YFS0110 Research and Development Projects of Sichuan Provincial Department of science and technology

Frantz tumors or solid pseudopapillary pancreatic neoplasm (SPN) are rare exocrine neoplasms that carry a favorable prognosis; they represent up to 3% of all tumors located in the region of the pancreas and have specific age and gender predispositions. In recent years, the rising curve of diagnosis is entitled to the evolution and access of diagnostic imaging. In this paper, we have retrospectively reviewed and described the clinical course of 40 patients with SPN from three institutions in Brazil, who had their diagnosis between 2005 and 2020, and analyzed the clinicopathological, genetic, and surgical aspects of these individuals. In accordance with the literature, most patients were women, 60% with unspecified symptoms at diagnosis, with tumors mainly located in the body and tail of the pancreas, of whom 70% underwent a distal pancreatectomy with sparing splenectomy as a standard procedure, and none of the cases have experienced recurrence to date. Surgery still remains the mainstay of treatment given the low metastatic potential, but more conservative approaches as observed in this cohort are evolving to become the standard of care. Herein, we present an in-depth analysis of cases focusing on the latest literature and report some of the smallest tumor cases in the literature. To our knowledge, this is the first report evaluating germline genetic testing and presenting a case of detected Li-Fraumeni syndrome.

The solid pseudopapillary epithelial neoplasm (SPN) is a rare form of pancreatic neoplasm with an incidence of 2-3% of all pancreatic tumours. The recent increase in incidence is attributed to the increasing use of imaging techniques for nonspecific abdominal complaints. We report our institutional experience in the management of this tumour over the last decade.

We retrospectively analyzed from a prospectively maintained database of patients from January 2011 to December 2020 who were operated upon for SPN. All the patients were followed till date.

Of 479 patients operated on for various types of pancreatic tumours during this period, 15 (3.1%) had SPN. The mean age of presentation was 28 years with a female preponderance (12/15, 80%). The most common location was the body and tail of the pancreas (66%), and the mean size was 6.4 cm (2–15 cm). The tumour extent was defined as ‘borderline resectable' in 20% of cases. Distal pancreatectomy was done in 11 patients with spleen preservation in 3. R0, R1, and R2 resection were done in 12, 2, and 1 patient(s), respectively. The operative mortality was 6.7%. All the patients are doing well on follow-up.

SPN is a low-grade malignant tumour with a strong female predilection. Clinical manifestations have no specificity, imaging examination only contributes tumour location, and the final diagnosis rests on pathology. Surgery is the main modality of treatment and carries a good prognosis.

• aggressive pancreatic cancer
• aggressive tumor
• pancreas
• pancreatic neoplasm
• solid pseudopapillary tumor

• Frantz
• Pseudopapillary
• case report
• neoplasms
• pancreas
• pancreatectomy

• Endoscopic ultrasound-guided fine-needle biopsy
• Neoplasm metastasis
• Pancreatic neoplasm

Exocrine pancreatic neoplasms represent up to 95% of pancreatic cancers (PCs) and are widely recognized among the most lethal solid cancers, with a very poor 5-year survival rate of 5%-10%. The remaining < 5% of PCs are neuroendocrine tumors that are usually characterized by a better prognosis, with a median overall survival of 3.6 years. The most common type of PC is pancreatic ductal adenocarcinoma (PDAC), which accounts for roughly 85% of all exocrine PCs. However up to 10% of exocrine PCs have rare histotypes, which are still poorly understood. These subtypes can be distinguished from PDAC in terms of pathology, imaging, clinical presentation and prognosis. Additionally, due to their rarity, any knowledge regarding these specific histotypes is mostly based on case reports and a small series of retrospective analyses. Therefore, treatment strategies are generally deduced from those used for PDAC, even if these patients are often excluded or not clearly represented in clinical trials for PDAC. For these reasons, it is essential to collect as much information as possible on the management of PC, as assimilating it with PDAC may lead to the potential mistreatment of these patients. Here, we report the most significant literature regarding the epidemiology, typical presentation, possible treatment strategies, and prognosis of the most relevant histotypes among rare PCs.

• Rare pancreatic cancers
• Pancreatic acinar cell cancer
• Pancreatic adenosquamous cancer
• Undifferentiated pancreatic cancer
• Pancreatoblastoma
• Pseudopapillary pancreatic cancer

To investigate the diagnosis, surgical treatment, and pathology of solid pseudopapillary tumors of the pancreas in our institution.

We retrospectively analyzed the demographic details, clinical features, imaging findings, and pathological findings of 87 patients with a confirmed diagnosis of solid pseudopapillary tumors of the pancreas (SPTP) and underwent surgery in Tongji Hospital of Tongji Medical College, over a period of 8 years from 2011 to 2018.

Our study involved a total of 87 patients (16 males and 71 females) with a mean age of 31.3±13.1 years (range: 10–61 years). The main compliant was abdominal pain or discomfort (n=49) and the median tumor size was 58.6±31.7 mm (range: 16–156mm). Tumors were located in the head (27 patients, 31%), the neck (13 patients, 15%), and the body and tail (47 patients, 54%). There were no significant differences between the patients in terms of sex, age, or tumor location. Partial pancreatectomy was performed in 79 patients, enucleation in six patients, and total pancreatectomy in two patients. R0 resection was achieved in 86 patients. The postoperative morbidity was 36.8%, and the main complication was pancreatic fistula. Pathological examination and immunohistochemical markers were used to provide a final diagnosis. The main follow-up period was 46 months (range: 13–97 months). At the end of the follow-up period, 86 patients were alive and had not experienced recurrence; one patient was lost to follow-up.

The accurate diagnosis of SPTP is vital. Our data showed that surgical resection is safe and associated with low morbidity and mortality rates. Pathological findings can play an important role in diagnosis and long-term survival.

• diagnosis
• pancreas
• solid pseudopapillary tumor
• surgical strategy

•

Solid pseudopapillary neoplasm with marked parenchymal atrophy of the distal pancreas.

Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare neoplasm, affecting primarily young females. Because SPNs are of low-malignancy, they rarely obstruct the main pancreatic duct (MPD) and cause atrophy of the distal pancreas even if their tumor sizes are large.

A 35-year-old female was referred to our hospital due to pancreatic tumor. Imaging findings showed the presence of well-defined round tumor in the body of the pancreas with 25-mm in diameter. The pancreas parenchyma distal to the tumor was markedly atrophic, and MPD dilatation was not observed. The lesion was diagnosed as SPN by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA), and central pancreatectomy was performed. Intraoperative frozen section of the distal atrophic pancreas showed no evidence of acinar cells, indicating exocrine dysfunction. Therefore, we closed distal pancreas stump instead of reconstruction. In the distal atrophic parenchyma, scattered foci of islets of Langerhans and the vestige of dilated MPD were observed. She has shown neither endocrine nor exocrine insufficiency after surgery.

SPNs are usually found without atrophic change of distal pancreas. To the best of our knowledge, this is the first report of SPN in which exocrine dysfunction of atrophic pancreas was demonstrated pathologically and central pancreatectomy without anastomosis of distal pancreas was chosen for the surgical treatment.

We reported a very rare case of SPN with marked distal parenchymal atrophy. We successfully performed central pancreatectomy without reconstruction.

• Case report
• Central pancreatectomy
• Exocrine dysfunction
• Parenchymal atrophy
• Solid pseudopapillary neoplasm

The role of progesterone receptor (PR) has been reported in a series of pancreatic cysts. However, the relationship between PR and prognosis of solid pseudopapillary neoplasm of the pancreas (SPNP) has not been elucidated so far. The aim of our study was to evaluate the prognostic value of PR in SPNP.

A total of 76 patients with SPNP treated in our institution from January 2012 to December 2017 were included. Demographic parameters, laboratory data, pathologic information and clinical outcomes were analyzed by the use of survival analysis. In addition, a pooled case series was performed to evaluate the results.

The institutional data included 76 patients (17 male and 59 female) ranging from 8 to 90 years (median, 30 years) in age. Kaplan-Meier survival analysis confirmed negative PR result was significantly associated with poorer disease-free survival (DFS) and disease-specific survival (DSS) (both P < 0.001). In the pooled analysis, a total of 62 studies comprising 214 patients with SPNP were included. After multivariable cox analysis, negative PR result remained an independent prognostic factor for SPNP (DFS HR: 14.50, 95% CI: 1.98–106.05, P = 0.008; DSS HR: 9.15, 95% CI: 1.89–44.17, P = 0.006).

Our results indicated the role of PR in predicting adverse outcome of patients with SPNP and negative PR result may serve as a potential prognostic factor.

The online version of this article (10.1186/s12876-018-0914-8) contains supplementary material, which is available to authorized users.

• Pancreas
• Progesterone receptor
• Prognosis
• Solid pseudopapillary tumor

• aggressive pancreas neoplasm
• pancreas neoplasm
• solid pseudopapillary neoplasm

• Carcinoma/diagnosis
• Carcinoma/physiopathology
• Humans
• Neoplasm Invasiveness
• Pancreatic Neoplasms/diagnosis
• Pancreatic Neoplasms/physiopathology
• Prognosis

• EGFR
• L861Q
• Solid-pseudo-papillary
• neoplasm
• pancreas

• Aggressive surgical resection
• Pancreas
• Solid pseudopapillary tumor

• Adenocarcinoma, Mucinous/drug therapy
• Adenocarcinoma, Mucinous/pathology
• Aged
• Antineoplastic Combined Chemotherapy Protocols/therapeutic use
• Carcinoma, Acinar Cell/drug therapy
• Carcinoma, Acinar Cell/pathology
• Carcinoma, Adenosquamous/drug therapy
• Carcinoma, Adenosquamous/pathology
• Carcinoma, Pancreatic Ductal/drug therapy
• Carcinoma, Pancreatic Ductal/pathology
• Cystadenocarcinoma, Mucinous/drug therapy
• Cystadenocarcinoma, Mucinous/pathology
• Humans
• Kaplan-Meier Estimate
• Middle Aged
• Pancreatic Neoplasms/drug therapy
• Pancreatic Neoplasms/pathology
• Prognosis
• Retrospective Studies
• Treatment Outcome

• cystic neuroendocrine tumors
• intraductal pancreatic mucinous neoplasm
• mucinous cystic neoplasm
• mucinous lesions
• pancreatic cystic lesions
• pancreatic ductal adenocarcinoma
• solid pseudo-papillary tumors

Solid pseudopapillary Carcinoma (SPC) is a rare pancreatic Tumor with variable, usually low, malignancy potential. Howewer, several SPC are associated with aggressive behavior, local vascular infiltration, organ invasion, distant metastasis, and can be unresectable. Irreversible Electroporation (IRE) is an emerging non-thermal ablation technique for the treatment of locally advanced pancreatic carcinoma. We report the results of four year disease-free follow-up in a case of locally advanced unresectable SPC treated with IRE.

A 24-year female patient with SPC of the pancreas underwent IRE during laparotomy under general anesthesia with intubation. Computed Tomography (CT) showed complete tumor thrombosis of splenic vein, encasement of celiac artery and mesenteric vein. Six insertions of 3–4 electrodes per insertion were performed. One month-CT-control showed shrinkage of the tumor. 6 months-post-treatment imaging showed complete regression of the mass, patent Splenic/mesenteric veins, absence of local recurrence or distant metastasis. Post treatment CTs at 12-18-24-30-36-42-48 months follow-up confirmed absence of local or distant recurrence.

Surgery is the first choice curative treatment of SPC. Howewer aggressive surgery (duodeno-pancreasectomy) in unresectable cases, may have a high risk of recurrences, morbidities and death, and bring concerns about endocrine and exocrine insufficiency in a young patient. In these cases, IRE could be a safe and effective alternative treatment and could realize, in selected cases, the condition for a radical surgery, and a bridge to R-0 resection.

IRE could represent an effective alternative therapy to surgery in local advanced, unresectable SPC.

•

Solid pseudopapillary Carcinoma (SPC) is a rare pancreatic Tumor with possible local vascular infiltration, distant metastasis, and can be unresectable.

• Case report
• Intraoperative ultrasound
• Irreversible electroporation
• Pancreatic neoplasm
• Solid papillary carcinoma

We aimed to investigate the metabolic characteristics of Solid pseudopapillary neoplasms (SPNs) in relation signal intensities on ¹⁸F-FDG PET scans.

SPNs of the pancreas commonly show high uptake of 18F-FDG. However, the metabolic characteristics underlying the high ¹⁸F-FDG uptake in SPNs are not well characterized.

mRNA expressions for glucose metabolism were analyzed in five SPNs, five pancreatic ductal adenocarcinomas (PCAs), and paired normal pancreatic tissues. Among the proteins involved in glucose metabolism, the expressions of five proteins (GLUT1, HK1, PFKM, ENO2, and PKM2) were evaluated in 36 SPNs by immunohistochemistry. Clinical patterns of SPN on PET scans were classified according to the proportion of ¹⁸F-FDG uptake within the whole tumor volume (hot: ≥ 70%, mixed: 30 ≤ < 70, and defective: < 30%). PET-based parameters, including maximum standardized uptake value (SUV_max) and metabolic tumor volume (TMV_2.5), were evaluated.

Hot (n = 19), mixed (n = 5), and defective (n = 12) ¹⁸F-FDG uptake patterns were noted in the 36 patients. Radiologic tumor size and SUV_max differed significantly according to these patterns (ANOVA, p < 0.05). GLUT1, HK1, PFKM, ENO2, and PKM2 were highly expressed in SPNs at both the mRNA and protein levels. Defective type SPNs showed lower expression of HK1 (p = 0.014), PKM2 (p = 0.028), and Ki-67 (p = 0.070) with frequent intra-tumoral necrosis (p = 0.007). High Ki-67 expression (≥ 3%) was associated with high SUV_max in pancreatic SPNs (p = 0.002).

SPN cells harbor an active molecular capacity for increased glucose metabolism. Especially, defective type SPNs were associated with low metabolic activity and related to low Ki-67 index.

• 18F-FDG-PET
• metabolism
• metabolomics
• pancreatectomy
• solid pseudopapillary neoplasm

• cancer intervention
• chemotherapy
• paediatric oncology
• paediatric surgery
• pancreatic cancer

• Adolescent
• Antineoplastic Agents/administration & dosage
• Carcinoma, Papillary/diagnostic imaging
• Carcinoma, Papillary/surgery
• Combined Modality Therapy
• Embolization, Therapeutic
• Female
• Humans
• Indoles/administration & dosage
• Liver Neoplasms/diagnostic imaging
• Liver Neoplasms/pathology
• Liver Neoplasms/secondary
• Liver Neoplasms/therapy
• Magnetic Resonance Imaging
• Pancreas/pathology
• Pancreatic Neoplasms/diagnostic imaging
• Pancreatic Neoplasms/surgery
• Pancreatic Neoplasms/therapy
• Pancreaticoduodenectomy
• Pyrroles/administration & dosage
• Sunitinib
• Tomography, X-Ray Computed
• Treatment Outcome

• 2-Deoxy-2-[(18)F] fluoro-d-glucose
• Computed tomography
• Magnetic resonance imaging
• Pancreas
• Positron emission tomography
• Solid pseudopapillary tumor

• X-ray computed
• diagnosis
• solid pseudopapillary tumor of the pancreas
• tomography

Solid pseudopapillary tumor (SPT) of the pancreas is a rare pathological condition, representing less than 3% of all exocrine pancreatic tumors. SPT usually occurs in young females, without notable symptoms, with a low malignant potential and excellent prognosis.

We conducted a retrospective study during the period January 2005 – January 2015. SPT patients admitted in our institution were reviewed by describing demographic data, clinico-pathologic and radiological features, therapeutic management and prognosis records.

Thirteen patients with SPT were identified (10 females), with a median age of 30 years. The main clinical presentation was abdominal pain (92.3%). The tumor was mostly located in the body or tail of the pancreas (77%), and the mean size was 8.2 cm. Regarding the surgical approach there were 5 distal pancreatectomies with splenectomy, 3 body and tail pancreatectomies, 2 body and tail pancreatectomies with splenectomy, 2 pancreato-duodenectomy, 1 partial enucleation and of all only 2 partial resections. Postoperative hematoxylin- eosin staining and immunohistochemistry confirmed the diagnosis in all cases. None of the patients had lymph nodes metastases. Only one local invasion. There was one case of death due to postoperative complications. Four cases followed adjuvant systemic chemotherapy. The mean follow-up was 18 months, without evidence of recurrence during this period.

SPT should always be considered in the differential diagnosis in young women with a pancreatic tumor. Complete surgical excision is the treatment of choice, and is usually curative. The decision to administer systemic therapy must be individualized. Malignant behavior and late recurrences mandates long-term follow-up for patients with SPT.

• SPT
• pancreas
• solid pseudopapillary tumor
• treatment

•

Solid pseudopapillary neoplasm is a rare pancreatic tumor.

Solid pseudopapillary neoplasm (SPN) is a rare pancreatic tumor. Most patients are female within the second or third decade of life with only a small minority concerning children. Frequently described as low malignant potential tumors, surgical resection remains the main treatment.

The authors present a case of a SPN diagnosed in a 17-year-old Caucasian girl with vomiting and abdominal pain localized to the right upper quadrant. CT scans and MRI scans showed the presence of a well-defined tumor arising from the pancreatic head with 14 cm of greater diameter. Pylorus-preserving pancreatoduodenectomy was performed and histopathology confirmed a SPN with complete resection and no evidence of malignancy.

SPN are usually found incidentally hence the importance of an accurate radiologic diagnosis. Symptoms may be present such as abdominal pain or vomiting due to compression, namely in large tumors. A surgical approach is usually indicated aiming complete resection, with tumor size not predicting resectability.

Solid pseudopapillary tumors of the pancreas are extremely rare and usually have an excellent long-term prognosis after surgical resection.

• Case report
• Frantz's tumor
• Pancreatic tumor
• Solid pseudopapillary neoplasm

• Solid pseudopapillary neoplasm pancreas

• SPN
• SPT
• cystic pancreatic neoplasm
• pancreas
• solid pseudopapillary neoplasms
• solid pseudopapillary tumors

• Adolescent
• Adult
• Aged
• Child
• Disease-Free Survival
• Female
• Humans
• Male
• Middle Aged
• Neoplasm Invasiveness
• Neoplasms, Glandular and Epithelial/mortality
• Neoplasms, Glandular and Epithelial/pathology
• Neoplasms, Glandular and Epithelial/surgery
• Pancreatectomy
• Pancreatic Neoplasms/mortality
• Pancreatic Neoplasms/pathology
• Pancreatic Neoplasms/surgery
• Retrospective Studies
• Treatment Outcome
• Young Adult

• optical diagnosis
• pancreatic solid pseudopapillary tumor
• two-photon excited fluorescence imaging
• unstained histological sections

• Coloring Agents
• Eosine Yellowish-(YS)
• Female
• Hematoxylin
• Humans
• Microscopy, Fluorescence
• Neoplasms, Glandular and Epithelial/diagnostic imaging
• Pancreatic Neoplasms/diagnostic imaging

To evaluate the clinical characteristics and radiological features of solid pseudopapillary tumor (SPT) and assess surgical therapy strategy.

A retrospective review was performed in 62 patients pathologically confirmed of SPT treated between 2003 and 2014. The clinical features, radiological examinations and surgical strategies were analyzed.

56 females and 6 males were included in this study, mean age was 26 years old (range: 8–66 years old) with mean size of the tumor was 7.2 cm (range: 3–15 cm), and most tumor were commonly located in the head of pancreas (n = 29). Among all the cases, 3 patients had liver metastasis and underwent resection of SPT and liver metastasis. Furthermore, we performed 29 cases of local tumor excision; other patients underwent pancreaticoduodenectomy, middle pancreatectomy, middle pancreatectomy with splenectomy, distal pancreatectomy with spleen preservation, distal pancreatectomy with splenectomy and duodenum-preserving pancreatic head resection. No patient suffered from lymph node metastases. After median follow-up of 46 months (range: 2–135 months), no mortality or local recurrence or distant metastasis was found.

Solid pseudopapillary tumor is a latent malignant tumor with excellent prognosis. If feasible, less aggressive resection without regular lymphadenectomy is recommended for treatment of patients with SPT.

• Adolescent
• Adult
• Aged
• Carcinoma, Papillary/diagnostic imaging
• Carcinoma, Papillary/surgery
• Child
• Demography
• Female
• Follow-Up Studies
• Humans
• Male
• Middle Aged
• Pancreatic Neoplasms/diagnostic imaging
• Pancreatic Neoplasms/surgery
• Preoperative Care
• Radiography, Abdominal
• Survival Analysis
• Treatment Outcome
• Young Adult

• Inconsistency
• Malignant
• Prognosis
• Solid pseudopapillary neoplasm

• chemotherapy
• hepatic arterial infusion
• liver metastasis
• resection
• solid pseudopapillary tumor
• transarterial tumor embolization

•

Pancreatic pseudopapillary tumor is an rarely problem.

Pseudopapillary tumors (PPT) of the pancreas are very rare, comprising 0.3–2.7% of all pancreatic tumors, and they occur mostly in young women. Generally, they are benign, but in rare cases they can enlarge, invade adjacent organs, and metastasize distantly. Radiological assessments and biochemical markers are important for diagnosing tumor characteristics. The main treatment is tumor resection.

An 18-year-old female was referred to our department suffering from abdominal discomfort and upper quadrant abdominal pain. Abdominal computed tomography (CT) revealed a 6- × 5-cm mass between the pancreatic head and right adrenal gland (Fig. 1). The histological assessment was a solid PPT of the pancreas with intact surgical borders.

PPT are very rare, comprising approximately 5% of cystic pancreatic tumors and ∼1% of exocrine pancreatic neoplasms and present mainly during the second and third decades of life. PPTs are usually indolent tumors. As such, they tend to produce vague nonspecific symptoms or may be detected incidentally on imaging. Complete surgical resection (R0) is the most effective therapy for PPT.

Although PPT is a very rare, benign tumor, it has the potential to metastasize to adjacent and distant organs. Consequently, they should be detected early, so that they can be treated surgically before malignant conversion.

• Enucleation
• Pancreas
• Pseudopapillary

• Adenomatous Polyposis Coli/diagnosis
• Adenomatous Polyposis Coli/pathology
• Adenomatous Polyposis Coli/surgery
• Adult
• Biopsy, Fine-Needle/methods
• Diagnosis, Differential
• Endoscopic Ultrasound-Guided Fine Needle Aspiration/methods
• Humans
• Male
• Pancreas/pathology
• Pancreatectomy/methods
• Pancreatic Neoplasms/diagnosis
• Pancreatic Neoplasms/pathology
• Pancreatic Neoplasms/surgery
• Pancreaticoduodenectomy
• Tomography, X-Ray Computed