Delayed perforation after endoscopic submucosal dissection for early gastric cancer: Clinical features and treatment

Table 1 Clinicopathological features and clinical outcomes in 16 patients with delayed perforation after endoscopic submucosal dissection

Case No.	Age	Sex	Location	Tumor size (mm)	Resected specimen size (mm)	Depth of tumor	Scar in tumor	Histological type	Time required for ESD (h)	Device	Time until peritonitis (h)	Size of perforation (mm)	Treatment of perforation	Hospital stay (d)
1	89	Male	L, Lc	84 × 50	102 × 73	SM1	Absent	Diff.	4	IT	> 24	3	Surgery	23
2	74	Male	L, Gc	17 × 10, 20 × 17	80 × 45 (2 lesions)	M	Absent	Diff.	2.4	IT2	10	-	Surgery	15
3	63	Male	R, P	15 × 12	28 × 28	M	Absent	Diff.	1.5	IT2	15	-	Surgery	30
4	83	Female	L, Lc	37 × 15	53 × 30	SM2	Present	Diff.	2.5	IT2	11	2	Surgery	23
5[4]	50	Female	U, Lc	20	50	M	Present	Diff.	3.5	IT2	24	20	Surgery	16
6[4]	60	Male	M, A	18	32	SM	Absent	Diff.	2	IT	19	-	Surgery	14
7[4]	70	Male	U, A	15	45	M	Absent	Diff.	3	IT	21	-	Conservative	15
8[4]	61	Male	U, P	50	85	SM	Absent	Diff.	9	IT	15	-	Surgery	33
9[4]	64	Female	U, Lc	12	50	M	Absent	Diff.	2.2	IT	23	-	Surgery	20
10[4]	64	Male	U, P	15	45	M	Present	Diff.	1.5	IT2	10	-	Surgery	12
11[13]	70	Female	R, Lc	5	30	M	Absent	Diff.	2	TT	> 24	-	Conservative	21
12[14]	60	Female	U, P	4	19	M	Absent	Signet	1.1	IT2	> 24	2	Endo clips	12
13[8]	70	Female	L, Gc	26	38	M	Absent	Diff.	0.5	IT	-	3	Endo clips	13
14[15]	60	Male	M, Gc	6 × 4	18 × 17	M	Absent	Diff.	0.4	-	10	1	Surgery	10
15[16]	64	Male	L, A	18 × 15	40 × 38	SM2	Present	Diff.	-	-	> 24 (49 d)	8	Surgery	-
16[9]	59	Female	L, A	10	-	M	Present	Diff.	0.4	-	> 24	20	Conservative	33

U: Upper body; M: Middle body; L: Lower body; R: Remnant stomach; Lc: Lesser curvature; P: Posterior; A: Anterior; Gc: Greater curvature; Diff.: Differentiated adenocarcinoma; Signet: Signet ring cell carcinoma; TT: Triangle-tip knife; ESD: Endoscopic submucosal dissection.