What is the impact of capsule endoscopy in the long term period?

Table 1 Capsule endoscopy findings in patients with obscure gastrointestinal bleeding

Findings	n (%)
Positive findings in CE	118 (84.9)
Normal	21 (15.1)
Angiodysplasia	27 (19.42)
Polypoid lesion	25 (17.98)
Ulcer	25 (17.98)
Erosions	22 (15.82)
Malign lesions	7 (5.12)
Active bleeding	4 (2.87)
Portal hypertensive enteropathy	2 (1.43)
Mucosal bleeding	2 (1.43)
Arteriovenous malformation	2 (1.43)
Diverticulum	1 (0.71)
Parasite infection	1 (0.71)

CE: Capsule endoscopy.

Table 2 Evalution of rebleeding according to the demographic data n (%)

		Rebleeding		P
		(+)	(-)
Age, n (%)	< 70 yr	32 (32)	68 (68)	10.001b
	> 70 yr	24 (61.5)	15 (38.5)
Comorbidity		33 (66)	17 (34)	20.001b
OGIB
Overt		42 (48.8)	44 (51.2)	20.015a
Occult		14 (26.4)	39 (73.6)
Vasculary lesion		31 (72.1)	12 (27.9)	20.001b
Positive capsule result		55 (46.6)	63 (53.4)	20.001b
NSAIDs-anticoagulant antiaggregant therapy		19 (73.1)	7 (26.9)	20.001b

¹Pearson Ki-kare test;

²Yates’ Continuity Correction test.

^aP < 0.05;

^bP < 0.01. OGIB: Obscure gastrointestinal bleeding; NSAIDs: Non-steroidal anti-inflammatory drugs.

Table 3 Risk factors for rebleeding (univariate-multivariate analysis)

	Univariate			Multivariate
	OR	95%CI	P	OR	95%CI	P
Comorbidity	5.176	2.442-10.972	0.001b	2.274	0.864-5.986	0.096
Age	3.400	1.574-7.342	0.001b	1.735	0.595-5.057	0.313
Overt OGIB	2.659	1.265-5.589	0.015a	1.222	0.490-3.048	0.667
NSAIDs-anticoagulant-antiagregant therapy	5.575	2.153-14.438	0.001b	5.843	1.868-18.275	0.002b
Vasculary lesion	6.458	2.852-14.625	0.001b	6.027	2.568-14.146	0.001b
Positive CE results	17.460	2.269-134.371	0.001b	-	-	-

^aP < 0.05;

^bP < 0.01. OGIB: Obscure gastrointestinal bleeding; NSAIDs: Non-steroidal anti-inflammatory drugs; CE: Capsule endoscopy.

Table 4 Rebleeding rates in different studies

Ref.	Total number of case	Follow-up duration (mo)	Rebleeding rates after negative CE (%)
Lai et al[11]	49	12	6
Macdonald et al[12]	49	17	11
Park et al[13]	51	32	36
Delvaux et al[14]	44	12	0
Iwamoto et al[16]	78	6	4
Lorenceau-Savale et al[17]	35	12	0
Koh et al[18]	51	23	23

CE: Capsule endoscopy.