Review
Copyright ©The Author(s) 2016.
World J Gastrointest Endosc. Jan 10, 2016; 8(1): 13-22
Published online Jan 10, 2016. doi: 10.4253/wjge.v8.i1.13
Table 1 Published literature reporting endoscopic through-the-scope clip closure for oesophageal perforations
Ref.CauseSize/mmTime to treatmentIm/Tm/TpMethodNrClinical successAdditional treatmentHospital stay /dFollow-up
Wewalka et al[7]Perforation (1)< 10< 24TmEndoclip1/1 (100%)NoneNDND
Rodella et al[44]Leak (7)10-20> 24NDEndoclipND2/7 (14%)YesND9.6 mo avg.
van Bodegraven et al[57]Fistula (1)12> 24NDEndoclip + argon beam electrocoagulationND1/1 (100%)YesND7 mo
Cipolletta et al[8]Perforation (2)7-8< 24Im/TmEndoclip11/1 (100%)No59 mo
10< 24Im/TmEndoclip21/1 (100%)No614 mo
Shimamoto et al[50]Perforation (1)20< 24TmEndoclip31/1 (100%)No37ND
Abe et al[58]Perforation (1)5> 24TmEndoclipND1/1 (100%)Yes36ND
Mizobuchi et al[59]Fistula (1)ND> 24TmEndoclip11/1 (100%)Yes> 31ND
Raymer et al[9]Fistula (3) ≤ 25> 24Tm/TpEndoclipND3/3 (100%)YesNDND
> 24Tm/TpEndoclip + surgeryNDYesNDND
> 24Tm/TpNDYesNDND
Shimizu et al[10]Perforation (3)8/10/2008< 24TmEndoclipND3/3 (100%)Yes14ND
Schubert et al[60]Leak (1)ND> 24TmStent + endoclipND1/1 (100%)NDND1 mo
Wehrmann et al[45]Perforation (4)ND> 24TmEndoclipND4/4 (100%)Yes9-2212 mo
Leak (3)ND> 24TmEndoscopic lavage + endoclipND3/3 (100%)Yes
Matsuda et al[46]Perforation (1)25< 24ImEndoclipND1/1 (100%)NoNDND
Sriram et al[11]Perforation (1)10> 24TmEndoclipND1/1 (100%)YesNDND
Fischer et al[61]Perforation (4)20-40< 24TmEndoclip2-64/4 (100%)No7-18No
< 24TmEndoclipNoNo
< 24TmEndoclipNoNo
< 24TmEndoclipNoNo
Gerke et al[62]Perforation (1)15< 24TmEndoclip3 + 11/1 (100%)No76 mo
Qadeer et al[28]Fistula (1)3> 24TmEndoclip + stent41/1 (100%)Yes6517 mo
Luigiano et al[56]Fistula (1)25> 24TmEndoclip51/1 (100%)NDND1 mo
Endoloop1
Ivekovic et al[55]Perforation (1)15 × 10 ≤ 24Im/TmEndoloop11/1 (100%)NDND4 wk
Endoclip4
Jung et al[63]Perforation (1)25> 24Im/TmEndoclip121/1 (100%)YesND2 mo
Endoloop1
Rokszin et al[47]Perforation (1)5-7< 24TpEndoclip31/1 (100%)Yes146 mo
Coda et al[64]Perforation (1)20 (distal)< 24TmEndoclip61/1 (100%)Yes156 mo
Sato et al[24]Perforation (1)ND< 24Im/TmEndoclipND1/1 (100%)NoNDND
Biancari et al[65]Perforation (4)8 (median)< 24TmEndoclipND3/4 (75%)Yes32 (median)No
Huang et al[66]Perforation (4)ND< 24NDEndoclip24/4 (100%)NDNDND
Table 2 Published literature reporting over-the-scope clip closure of oesophageal perforations
Ref.CauseSize/mmTime to treatment (< 24 h <)Im/Tm/TpMethodNrClinical successAdditional treatmentHospital stay /dFollow-up
Pohl et al[67]Leak (1)< 0> 24TpOTSC11/1(100%)No30ND
Perforation (1)ND> 24TpSurgery + stent + OTSC0/1(0%)YesDiedND
von Renteln et al[68]Fistula (2)ND> 24TmOTSC10/2(0%)NDNDND
ND> 24TmOTSC1YesNDND
Traina et al[69]Fistula (1)ND> 24TmOTSC11/1(100%)NDND4 wk
Albert et al[70]Fistula (1)ND> 24TmOTSC11/1(100%)NDND46 wk
Leak (1)ND> 24TmOTSC10/1(0%)StentND4 wk
Leak (1)ND> 24TmOTSC11/1(100%)NDND63 wk
Kirschniak et al[71]Leak (1)ND> 24NDOTSCND1/1(100%)ND10ND
Manta et al[72]Fistula (1)8 × 4> 24TmOTSC + standard clips1+31/1(100%)No0ND
Surace et al[73]Leak (1)ND> 24NDOTSCND1/1(100%)NDNDND
Baron et al[41]Leak (3)ND> 24TmOTSC41/3(33%)NDND77 avg. (30-330 d)
Perforation (1)ND< 24Tm1/1(100%)NDND
Hadj Amor et al[74]Perforation (1)20< 24TpOTSC + stent11/1(100%)VATSNDND
Hagel et al[53]Leak (2)28 × 13> 24Tm/TpOTSC31/2(50%)SurgeryDied30 d
8 × 4No12.3 ± 1130 d
Perforation (2)8 × 3> 24Tm/TpOTSC10/2(0%)Surgery30 d
14 × 3> 24Surgery30 d
Jacobsen et al[75]Perforation (3)9> 24NDOTSC23/3(100%)NoNDND
10 (distal)> 24ND1NoNDND
10> 24ND2NoNDND
Markar et al[76]Leak (1)ND> 24TmOTSC21/1(100%)YesND3 mo
Voermans et al[40]Perforation (5)< 30< 24NDOTSCND5/5(100%)NoND6 mo
Zolotarevsky et al[77]Fistula (1)5> 24NDOTSCND1/1(100%)ND73 mo
Braun et al[43]Perforation (6)10-40< 24Tm/TpOTSC1-46/6(100%)VATS9-196-12 wk
Ferreira et al[51]Perforation (1)10 (distal)> 24TmOTSC11/1(100%)No213 mo
Noronha Ferreira et al[78]Leak (1)10 × 6> 24TmOTSC11/1(100%)No14ND
Nishiyama et al[79]Perforation (1)20> 24NDOTSCND1/1(100%)NDND56 d
Ramhamadany et al[49]Perforation (1)ND> 24NDOTSCND1/1(100%)YesND6 mo
Bona et al[48]Perforation (1)10> 24Tm/TpOTSC11/1(100%)No28No
Haito-Chavez et al[42]Perforation (10)ND< 24Tm/TpOTSC10/10(100%)NDNDMedian follow-up: 121-207 d
Leaks (5)ND> 24Tm/Tp4/5(80%)NDND
Fistula (16)ND> 24Tm/Tp9/16(57%)NDND
Mönkemüller et al[52]Fistula (4)10-15> 24NDOTSC1-22/4(50%)NoND10 mo (1-10)
Leak (1)10-12> 24NDOTSC0/1(0%)NoND