Diagnosis of small intramucosal signet ring cell carcinoma of the stomach by non-magnifying narrow-band imaging: A pilot study

Table 1 Characteristics of signet ring cell carcinoma patients and controls

	SRC	Control	P value
Age, yr, mean ± SD	53.2 ± 14.2	69.1 ± 14.8	0.0008
Sex, male/female	7/6	10/4	0.44
Location: upper/middle/lower	2/7/5	4/8/2	0.36
NBI finding
NBI index (mean ± SD)	27.9 ± 21.0a	24.8 ± 14.7	0.78
H. pylori: positive/negative	26.1 ± 20.5/29.0 ± 22.4	27.8 ± 15.4/19.3 ± 13.2	0.95 in SRC and 0.26 in control
WLI finding (mean ± SD)
WLI index	5.3 ± 16.2a	-	0.001a
H. pylori: positive/negative	13.5 ± 16.4/0.7 ± 15.1	-	0.32
C-index (mean ± SD)	0.67 ± 0.13	0.50 ± 0.14	0.001

^aP = 0.001 between NBI index and WLI index. SRC: Signet ring cell carcinoma; NBI: Narrow-band imaging; WLI: White light imaging; C-index: Circularity index.

Table 2 Characteristics of signet ring cell carcinomas in the 13 patients

Case	Age	Sex	Type	Size (mm)	Location	Location	Hp	PDE	NBI index	WLI index	C-index	Endoscopic system
1	23	Female	IIb	4	M	GC	+	-	22.5	3.5	0.75	CV-260 SL
			IIc	6	L	GC		-	25.6	16.1	0.67	CV-290
2	63	Female	IIb	14	M	LC	+	+	5.5	2.2	0.76	CV-260 SL
3	62	Male	IIc	15	M	GC	+	-	16.8	41.1	0.61	CV-260 SL
4	74	Female	IIc	4	U	GC	+	+	60.2	4.5	0.63	CV-260 SL
5	48	Male	IIc	4	L	GC	-	-	59.6	0.22	0.66	CV-260 SL
6	62	Male	IIb	5	M	LC	-	+	17.6	-2.7	0.81	CV-260 SL
7	48	Male	IIc	2	U	GC	-	-	1.0	4.0	0.33	CV-260 SL
8	58	Male	IIc	5	L	LC	-	-	19.5	-33.7	0.88	CV-260 SL
9	40	Female	IIb	6	M	GC	-	-	25.6	12.8	0.77	CV-290
10	69	Female	IIb	8	L	PW	-	-	68.5	-8.5	0.60	CV-290
11	46	Male	IIb	5	M	GC	-	-	10.8	9.3	0.63	CV-290
12	60	Male	IIb	6	M	GC	-	-	19.7	16.3	0.57	CV-290
13	38	Female	IIb	6	L	PW	-	-	38.2	8.7	0.69	CV-290

Hp: Helicobacter pylori; PDE: Partially defect of epithelium; L: Lower third of the stomach; M: Middle third of the stomach; U: Upper third of the stomach; GC: Greater curvature; LC: Lesser curvature; PW: Posterior wall; C-index: Circularity index; NBI: Narrow-band imaging; WLI: White light imaging.