Retrospective Study
Copyright ©The Author(s) 2015.
World J Gastrointest Endosc. Aug 10, 2015; 7(10): 995-1002
Published online Aug 10, 2015. doi: 10.4253/wjge.v7.i10.995
Table 1 Patient level summary of polyp histology
Polyp’s typeTotal patients (n = 296)Percentage
Hyperplastic polyp8729.39
Fundic gland polyp8227.7
Chronic gastritis4113.85
Mixed134.39
Intestinal metaplasia124.05
Foveolar hyperplasia103.38
Adenoma51.69
Carcinoid tumor41.35
Granulation tissue polyp41.35
Adenocarcinoma20.68
Gastric xanthelasma20.68
Hamartomatous polyp20.68
Lymphoid follicles20.68
Submucosal Brunner glands20.68
Lipoma10.34
Normal279.12
Table 2 Distribution of patient and clinical characteristics according to different polyp types n (%)
CofactorAdenoman = 5Fundicn = 82Hyperplasticn = 87Mixedn = 13Othern = 109P value
Age (yr), mean ± SD75.4 (3.3)54.7 (13.0)58.4 (10.8)62.2 (14.0)57.7 (11.9)0.0013
Gender0.2086
Female5 (100.0)67 (81.71)64 (73.56)9 (69.23)75 (68.81)
Male0 (0.00)15 (18.29)23 (26.44)4 (30.77)34 (31.19)
Ethnicity0.7427
Hispanic5 (100.0)66 (80.49)77 (88.51)11 (84.62)93 (85.32)
Non-Hispanic White0 (0.00)5 (6.10)4 (4.60)0 (0.00)8 (7.34)
Other0 (0.00)11 (13.41)6 (6.90)2 (15.38)8 (7.34)
Pathology of surrounding gastric< 0.00011
Chronic gastritis0 (0.00)51 (62.20)52 (59.77)9 (69.23)78 (41.05)
Intestinal metaplasia3 (60.00)1 (1.22)6 (6.90)1 (7.69)14 (56.00)
Other0 (0.00)22 (26.83)15 (17.24)2 (15.38)5 (16.67)
Not biopsied2 (40.00)8 (9.76)14 (16.09)1 (7.69)12 (23.53)
Helicobacter pylori status0.00061
Negative4 (80.00)70 (85.37)52 (59.77)11 (84.62)74 (35.07)
Positive0 (0.00)8 (9.76)27 (31.03)2 (15.38)34 (47.89)
Not tested1 (20.00)4 (4.88)8 (9.20)0 (0.00)1 (7.14)
Portal hypertensive gastropathy0.1821
No5 (100.0)80 (97.56)77 (88.51)12 (92.31)102 (93.58)
Yes0 (0.00)2 (2.44)10 (11.49)1 (7.69)7 (6.42)
Table 3 Unadjusted and adjusted associations of cofactors with Helicobacter pylori positive status (n = 262)
CofactorUnadjusted OR(95%CI), P valueAdjusted OR(95%CI), P value
Age (yr)1.011 (0.988-1.034), 0.3686
Polyp type
Fundic (referent)11
Hyperplastic4.621 (1.918-11.133), 0.00064.621 (1.861-11.479), 0.0010
Other3.469 (1.509-7.976), 0.00342.952 (1.250-6.972), 0.0136
Gender
Female (referent)1
Male0.891 (0.460-1.726), 0.7321
Ethnicity
Hispanic (referent)1
Non-hispanic White0.205 (0.026-1.605), 0.1311
Other0.409 (0.117-1.435), 0.1629
Pathology of surrounding gastric
Chronic gastritis (referent)11
Intestinal metaplasia0.996 (0.407-2.437), 0.99310.827 (0.331-2.065), 0.6848
Other0.088 (0.021-0.375), 0.00100.090 (0.021-0.390), 0.0013
Portal hypertension
No (referent)1
Yes0.569 (0.159-2.044), 0.3877
Table 4 Unadjusted and adjusted associations of cofactors with hyperplastic polyps as compared with fundic polyps (n = 143)
CofactorUnadjusted OR(95%CI), P valueAdjusted OR(95%CI), P value
Age (yr)1.031 (1.001-1.062), 0.0419
H. pylori status
Negative (referent)11
Positive4.622 (1.918-11.137), 0.00065.285 (2.166-12.892), 0.0003
Gender
Female (referent)1
Male1.804 (0.756-4.303), 0.1837
Ethnicity
Hispanic (referent)1
Non-Hispanic White0.469 (0.083-2.655), 0.3922
Other0. 536 (0.150-1.923), 0.3390
Pathology of surrounding gastric
Chronic gastritis (referent)1
Intestinal metaplasia5.997 (0.697-51.614), 0.1029
Other0.714 (0.331-1.542), 0.3917
Portal hypertension
No (referent)11
Yes5.080 (1.057-24.414), 0.04246.903, 0.0174