Copyright ©2014 Baishideng Publishing Group Co.
World J Gastrointest Endosc. Apr 16, 2014; 6(4): 121-127
Published online Apr 16, 2014. doi: 10.4253/wjge.v6.i4.121
Table 1 Contrast agents for ultrasonography[7]
Contrast agentCompositionManufacturer
First generation
Albunex5% Sonicated serum albumin with stabilized microbubblesMallinckrodt
Echovist (SHU 454)Standardized microbubbles with galactose shellSchering
Levovist (SHU 508)Stabilized, standardized microbubbles with galactose, 0.1% palmitic acid shellSchering
MyomapAlbumin shellQuadrant
QantisonAlbumin shellQuadrant
SonavistCyanoacrylate shellSchering
Second generation
Definity/luminityC3F8 with lipid stabilizer shellBristol-Myers Squibb Medical Imaging
SonazoidC4F10 with lipid stabilizer shellGE Healthcare
Imagent-ImavistC6F14 with lipid stabilizer shellAlliance
OptisonC3F8 with denatured human albumin shellGE Healthcare
Bisphere/cardiospherePolylactide-coglycolide shell with albumin overcoatCommercially unavailable
SonoVueSF6 gas with lipid stabilizer shellBracco
AI700/imagifyC4F10 gas core stabilized with polymer shellAcusphere
Third generation
EchogenDodecafluoropentane (DDFP) liquid in phase shift colloid emulsionSonus Pharmaceuticals