Single operator choledochoscopy and its role in daily endoscopy routine

Table 1 Overview about the sensitivity and specificity of SpyGlass

First author, publication, year	Study design	Patient (n)	Sensitivity for visual diagnosisual diagnosis/biopsy	Specificity for visual diagnosis/biopsy	PPV for visual diagnosis/biopsy	NPV for visual diagnosis/biopsy	Accuracy for biopsy/visual diagnosis
Chen[15], 2007	Prospective study	35	100%/71%	77%/100%	70%/100%	100%/87%
Ramchandani et al, 2012	Prospective study	36	95%/82%	79%/82%	88%/100%	92%/100%	89%/82%
Hartmann et al, 2012	Retrospective analysis	89	/57%	/100%	/100%	/68%	/78%
Chen et al, 2011	Prospective study	297	77.8%/48.9%	82%/98%	80%/100%	80%/72%	80%/75%
Kalaitzakis et al, 2012	Retrospective analysis	141	72%	97%	93%	86%	88%

PPV: Positive predictive value; NPV: Negative predictive value.