Concise review on the comparative efficacy of endoscopic ultrasound-guided fine-needle aspiration vs core biopsy in pancreatic masses, upper and lower gastrointestinal submucosal tumors

Table 1 Summary of efficacy and safety of endoscopic ultrasound-guided fine needle aspiration with or without biopsy procedures

Procedure	Diagnostic accuracy	Safety (complications)	Mortality
Pancreatic, upper and lower GIST: Gastrointestinal stromal tumors; Submucosal tumors1
EUS-FNA	Variable	Low	None
ROS available	High
ROS unavailable	Low-moderate
EUS-FNB	High	Low
Other gastrointestinal lesions (lymphoma, GIST and chronic pancreatitis)
EUS-FNA	Low	Low	None
EUS-FNB	High	Low

¹Excluding lymphoma, GIST and chronic pancreatitis. ROSE: Rapid on-site evaluation; GIST: Gastrointestinal stromal tumors; EUS: Endoscopic ultrasound; FNA: Fine needle aspiration; FNB: Fine needle biopsy.