White light endoscopy, narrow band imaging and chromoendoscopy with magnification in diagnosing colorectal neoplasia

doi:10.4253/wjge.v1.i1.45

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Oct 15, 2009 (publication date) through May 10, 2024

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World Journal of Gastrointestinal Endoscopy

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1948-5190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Endosc. Oct 15, 2009; 1(1): 45-50
Published online Oct 15, 2009. doi: 10.4253/wjge.v1.i1.45

Table 1 Accuracy of various imaging modalities in the prediction of polyp histology

	WLE	NBI (KPP)	NBI (MBCN)	NBI (COMB)	CHR
Hyperplastic (7)	1	2	7	7	5
Adenomatous (38)	28	36	36	36	35
Carcinoma (5)	4	5	4	5	5
Total (50)	33	43	47	48	45

Table 2 The Sn, Sp, PPV and NPV looking individually at the performances of each modality compared to the final histopathological diagnosis (95% CI)

	Sn	Sp	PPV	NPV
WLE
HP	14.3 (2.6, 51.3)	97.7 (87.9, 99.6)	50 (9.5, 90.5)	87.5 (75.3, 94.1)
A	73.7 (58.0, 85.0)	91.7 (64.6, 98.5)	96.6 (82.8, 99.4)	52.4 (32.4, 71.7)
C	80.0 (37.6, 96.4)	97.8 (88.4, 99.6)	80 (37.6, 96.4)	97.8 (88.4, 99.6)
Overall	94.1 (80.9, 98.4)	6.3 (1.1, 28.3)	68.1 (53.8, 79.6)	33.3 (6.1, 79.2)
NBI (KPP)
HP	28.6 (8.2, 64.1)	100 (91.8, 100)	100 (34.2, 100)	89.6 (77.8, 95.5)
A	94.7 (82.7, 98.6)	100 (75.8, 100)	100 (90.4, 100)	85.7 (60.1, 96.0)
C	100 (56.6, 100)	97.8 (88.4, 99.6)	83.3 (43.6, 97.0)	100 (92.0, 100)
Overall	100 (91.4, 100)	22.2 (6.3, 54.7)	85.4 (72.8, 92.8)	100 (34.2, 100)
NBI (MCBN)
HP	100 (64.6, 100)	97.7 (87.9, 99.6)	87.5 (52.9, 97.8)	100 (91.6, 100)
A	94.7 (82.7, 98.6)	91.7 (64.6, 98.5)	97.3 (86.2, 99.5)	84.6 (57.8, 95.7)
C	80.0 (37.6, 96.4)	97.8 (88.4, 99.6)	80.0 (37.6, 96.4)	97.8 (88.4, 99.6)
Overall	95.2 (84.2, 98.7)	87.5 (52.9, 97.8)	97.6 (87.4, 99.6)	77.8 (45.3, 93.7)
NBI (COMBINED)
HP	100 (64.6, 100)	97.7 (87.9, 99.6)	87.5 (52.9, 97.8)	100 (91.6, 100)
A	94.7 (82.7, 98.6)	100 (75.8, 100)	100 (90.4, 100)	85.7 (60.1, 96.0)
C	100 (56.6, 100)	97.8 (88.4, 99.6)	83.3 (43.6, 97.0)	100 (92, 100)
Overall	97.6 (87.7, 99.6)	87.5 (52.9, 97.8)	97.6 (87.7, 99.6)	87.5 (52.9, 97.8)
CHR
HP	71.4 (35.9, 91.8)	97.7 (87.9, 99.6)	83.3 (43.6, 97.0)	95.5 (84.9, 98.7)
A	92.1 (79.2, 97.3)	100 (75.8, 100)	100 (90.1, 100)	80.0 (54.8, 93.0)
C	100 (56.6, 100)	97.8 (88.4, 99.6)	83.3 (43.6, 97.0)	100 (92.0, 100)
Overall	97.6 (87.4, 99.6)	55.6 (26.7, 81.1)	90.9 (78.8, 96.4)	83.3 (43.6, 97.0)

Sn: Sensitivity; Sp: Specificity; PPV: Positive predictive value; NPV: Negative predictive value; HP: Hyperplastic polyp; A: Adenomatous polyp; C: Carcinoma.

Citation: Singh R, Owen V, Shonde A, Kaye P, Hawkey C, Ragunath K. White light endoscopy, narrow band imaging and chromoendoscopy with magnification in diagnosing colorectal neoplasia. World J Gastrointest Endosc 2009; 1(1): 45-50
URL: https://www.wjgnet.com/1948-5190/full/v1/i1/45.htm
DOI: https://dx.doi.org/10.4253/wjge.v1.i1.45