Copyright ©The Author(s) 2015.
World J Gastrointest Endosc. Feb 16, 2015; 7(2): 102-109
Published online Feb 16, 2015. doi: 10.4253/wjge.v7.i2.102
Table 1 Pharmacologic profile of commonly used drugs for procedural sedation
DrugsOnset of action (min)Duration of action (min)Usual dosesFDA pregnancy categoryAdverse effects
Pethidine3-660-18025-100 mgCRespiratory depression, vomiting
Fentanyl1-230-6050-200 μgCRespiratory depression, vomiting
Alfentanyl< 130-600.250-2 mgCRespiratory and cardiovascular depression
Midazolam1-215-801-6 mgDRespiratory depression, disinhibition
Propofol< 14-840-400 mgBRespiratory and cardiovascular depression
Flumazenil1-2600.1-1 mgCAgitation, withdrawal symptoms
Naloxone1-230-450.2-1 mgBNarcotic withdrawal