Cell-block procedure in endoscopic ultrasound-guided-fine-needle-aspiration of gastrointestinal solid neoplastic lesions

Figure 1 Cell block from gastrointestinal stromal tumour exhibiting aggregates of spindle cells with elongated nuclei (haematoxylin-eosin, × 200) (A), with an evident immunoreactivity for CD117 (immunoperoxidase, × 200, Mayer’s Haemalum nuclear counterstain) (B).

Figure 2 Spindle cells of gastric gastrointestinal stromal tumour documented only a sporadic nuclear Ki67 immunopositivity (immunoperoxidase, × 400, Mayer’s Haemalum nuclear counterstain) (A) in benign contaminant gastrointestinal cells, the apical cytoplasm showed a peculiar CD10 immunoreactivity (immunoperoxidase, × 400, Mayer’s Haemalum nuclear counterstain) (B).

Figure 3 Well differentiated pancreatic carcinoma with a pseudo-glandular pattern (haematoxylin-eosin, × 400) (A), a nuclear strong p53 immunostaining was encountered in neoplastic elements (immunoperoxidase, × 400, Mayer’s Haemalum nuclear counterstain) (B).

Figure 4 Peripheral cholangiocarcinoma with a papillary pattern (haematoxylin-eosin, × 400) (A), in a serial section obtained from CBP neoplastic elements exhibited an evident cytokeratin 7 immunoreaction (B) (immunoperoxidase, × 400, Mayer’s Haemalum nuclear counterstain).