Novel serine/threonine kinase 11 gene mutations in Peutz-Jeghers syndrome patients and endoscopic management

Figure 1 Each pedigree of the three families with Peutz-Jeghers syndrome.

Figure 2 Sites of primers which are employed for polymerase chain reaction and direct sequencing to assess germline mutations of serine/threonine kinase 11 gene.

Figure 3 Narrow-band imaging-magnification gastroscopic picture. A: Narrow-band imaging (NBI)-magnification gastroscopic picture showing type A of the classification; B: NBI-magnification colonoscopic picture showing type B of the classification.

Figure 4 Serine/threonine kinase 11 germline mutation of +658C>T in exon5 that was identified in all the 3 Peutz-Jeghers syndrome patients in Family I.