Retrospective Cohort Study
Copyright ©The Author(s) 2017.
World J Hepatol. Mar 18, 2017; 9(8): 427-435
Published online Mar 18, 2017. doi: 10.4254/wjh.v9.i8.427
Table 1 Patient characteristics directly before transplantation
Patients who survived (n = 68)Patients who died (n = 46)P-value (χ2 test)
Male39 (57%)31 (67%)NS
Age, yr (median, SD)16-65 (50.5, 13)17-69 (56.0, 12)0.009
BMI, range kg/m2 (median, SD)18-33 (23.1, 3)15-29 (25.9, 4)0.029
Pre-LTx creatinine, mg/dL (median, SD)0.4-3.5 (1.0, 0.5)0.3-2.9 (1.1, 0.6)NS
GFR, mL/min (median, SD)15.3-230.2 (73.3, 38.1)22.6- 240.4 (62.5, 48.0)NS
ALT, U/L (median, SD)4-2610 (35.5, 449.5)6-1566 (19.5, 339.0)NS
Gamma-GT, U/L (median, SD)7-374 (47.0, 8)13-184 (43.0, 45)NS
Bilirubin, mg/dL (median, SD)0.4-28.1 (2.4, 5.7)0.4-28.3 (2.4, 5.8)NS
Warm ischemia time, min (median, SD)25-100 (50.0, 18)22-75 (54.0, 15)NS
Cold ischemia time, min (median, SD)242-940 (542.5, 157)174-825 (521.0, 146)NS
Donor age, yr (median, SD)12-70 (36.5, 16)13-75 (41.0, 1)NS
Donor BMI, kg/m2 (median, SD)17-30 (23.5, 3)18-31 (24.2, 2)NS
Underlying diagnosis n (%)
HCC2 (3)3 (6)NS
Alcohol toxic liver cirrhosis12 (18)13 (27)NS
PSC4 (6)2 (4)NS
Autoimmune5 (8)2 (4)NS
HCV cirrhosis9 (14)6 (13)NS
HBV infection16 (24)5 (10)0.049
Other18 (27)17 (35)NS
Table 2 Comparison of survival according to age, body mass index and hepatitis B virus status in a Eurotransplant control cohort (n = 2973)1
Patients who survived n (%)Patients who died n (%)P-value (χ2 test)
Age below 53 yr (n = 1809)1156 (64)653 (36)
Age above 53 yr (n = 1145)520 (45)625 (55)< 0.001
BMI below 24 kg/m2 (n = 1454)880 (61)574 (39)
BMI above 24 kg/m2 (n = 1493)796 (53)697 (47)< 0.001
Hepatitis B as underlying disease (n = 255)170 (67)85 (33)
Non-hepatitis B patients (n = 1705)946 (55)759 (45)< 0.001