Observational Study
Copyright ©The Author(s) 2016.
World J Hepatol. Nov 28, 2016; 8(33): 1459-1465
Published online Nov 28, 2016. doi: 10.4254/wjh.v8.i33.1459
Table 1 Differences between non-alcoholic-fatty-liver-disease and control patients
NAFLD (n = 532)Controls (n = 667)P vaule
Age, yr48.11 ± 9.0048.60 ± 8.70 0.343
Systolic blood pressure (mmHg)124.53 ± 9.71121.21 ± 10.80< 0.0001
Diastolic blood pressure (mmHg)78.84 ± 6.7276.50 ± 6.73< 0.0001
BMI, kg/m230.49 ± 5.5524.44 ± 3.72< 0.0001
HOMA2.89 ± 1.761.80 ± 1.28< 0.0001
eGFR82.49 ± 14.1582.15 ± 17.44 0.714
Total cholesterol, mg/dL205.17 ± 37.16207.09 ± 38.82 0.387
HDL cholesterol, mg/dL51.67 ± 15.8561.45 ± 16.41< 0.0001
Triglycerides, mg/dL109.08 ± 42.4195.23 ± 58.59< 0.0001
LDL cholesterol, mg/dL131.98 ± 33.45126.59 ± 37.29 0.009
γ-GT (U/L)33.24 ± 29.4026.03 ± 21.95< 0.0001
AST (U/L)20.77 ± 5.9121.01 ± 7.10 0.530
ALT (U/L)15.65 ± 4.6010.40 ± 4.88< 0.0001
Alkaline phosphatase (U/L)68.37 ± 18.4972.75 ± 43.42 0.030
Serum albumin (g/dL)4.62 ± 0.394.53 ± 0.40< 0.0001
Lifestyle items
AMDS32.21 ± 0.9134.91 ± 0.61< 0.0001
Baecke - physical activity total score39.82 ± 3.6041.43 ± 3.32< 0.0001
Western diet score22.84 ± 7.8712.73 ± 2.48< 0.0001
Sun exposure score31.43 ± 3.8935.73 ± 5.25< 0.0001
Sleep hours7.86 ± 1.317.90 ± 1.23 0.552
Table 2 Pearson’s χ2 and odds ratio
NAFLDControlsχ2P valueOR95%CI
BMI ≥ 26.40408167316.3851< 0.00019.8517.546-12.861
BMI < 26.40124500
HOMA ≥ 1.87368211167.0111< 0.00014.8493.792-6.202
HOMA < 1.87164456
HDL ≥ 54.5020440055.3581< 0.00010.4150.329-0.524
HDL < 54.50328267
TGL ≥ 9432424073.7751< 0.00012.7712.191-3.506
TGL < 94208427
AMDS ≥ 34326501008.8311< 0.00010.0020.001-0.003
AMDS < 3450017
BAECKE ≥ 41.518135443.4681< 0.00010.4560.360-0.577
BAECKE < 41.5351313
WDS ≥ 15.539997445.9811< 0.000117.62913.174-23.590
WDS < 15.5133570
SES ≥ 34.5111348122.7881< 0.00010.2420.187-0.313
SES < 34.5421319
Sleep hours ≥ 83193702.59210.1071.2100.959-1.527
Sleep hours < 8208292
Table 3 Multiple linear regression of variables
PredictorsRR2FSig.βP value
0.9650.9322309.1< 0.0001
BMI, kg/m2-0.448< 0.0001
HOMA-0.393< 0.0001
AMDS-1.398< 0.0001
Baecke-0.074< 0.0001
WDS0.069< 0.0001
Sun exposure score-0.044< 0.0001
Sleep hours-0.0080.296