Liver ultrasound elastography: More than staging the disease

Table 1 Use of ultrasound elastography to predict liver disease related complications

Ref.	Method	Cut-off value	Sensitivity	Specificity	AUROC
Elastography to predict significant portal hypertension
Zhang et al[21]	TE	13.6 kPa	83.87%	72.53%	0.83
Salzl et al[24]	TE	16.8 kPa	89.75%	75%	0.87
Salzl et al[24]	ARFI	2.58 m/s	71.4%	87.5%	0.85
Carrión et al[25]	TE	8.74 kPa	90%	81%	0.94
Elastography to predict the presence of esophageal varices
Vizzutti et al[18]	TE	17.6 kPa	90%	43%	0.76
Castéra et al[26]	TE	21.5 kPa	76%	78%	0.86
Kazemi et al[27]	TE	19 kPa	84%	70%	0.84
Pár et al[28]	TE	19.2 kPa	85%	87%	0.88
Elastography to predict hepatocellular carcinoma
Feier et al[34]	TE	38 kPa	51.7%	90.4%	0.68
Wong et al[33]	TE (part of a score)	-	-	-	0.83-0.89
Elastography to predict the liver related death of the patients with liver cirrhosis
			Rate of death
Pang et al[38]	TE	40 kPa	34%/3 yr
de Lédinghen et al[39]	TE	< 9 kPa	2.9%/5 yr
		> 20 kPa	38.5%/5 yr

TE: Transient elastography (fibroscan); ARFI: Acoustic radiation force impulse imaging.