Early termination of immune tolerance state of hepatitis B virus infection explains liver damage

Table 1 Baseline characteristics of study population

Parameters
Total number of patients	81
Male	60a (74%)
Female	21 (26%)
Age (yr)	17.5 ± 2.8 (12-20)
ALT ≤42 (U/L)	52a (65.2%) (13-42)
ALT > 42 (U/L)	29 (34.8%) (44-281)
DNA ≤100000 (copies/mL)	57a (70.4%)
DNA > 100000 (copies/mL)	24 (29.6%)
Non-significant hepatic necroinflammation(HAI-NI ≤7)	44 (53.8%)
Significant hepatic necroinflammation(HAI-NI > 7)	37 (45.7%)
Non-significant hepatic fibrosis (HAI-F < 3)	66a (81%)
Significant hepatic fibrosis (HAI-F≥3)	15 (18.5%)
Cirrhosis	2/15

Figure in the round bracket indicates the percentage and the square bracket indicates range.

^aP < 0.05 vs same parameter. HAI-NI: Histologic activity index-necroinflamation; ALT: Alaninaminotransferase; HAI-F: Histologic activity index-fibrosis.