Complementary and alternative medications in hepatitis C infection

Table 1 Herbal supplements to discontinue and/or avoid while taking hepatitis C virus treatment

Herbal Product	Effect
Milk thistle (Silybum marianum)	Concomitant use of milk thistle may result in increased plasma concentrations of simeprevir
St. John’s wort (Hypericum perforatum)	Concomitant use of St. John’s wort may result in decreased plasma concentrations of telaprevir, boceprevir, simeprevir and sofosbuvir