Elevated liver enzymes portends a higher rate of complication and death in SARS-CoV-2

Table 1 Patient demographics

Variable	Response	All patients (n = 8028)
Sex	Female	4638 (58%)
	Male	3389 (42%)
	Unknown	1 (0%)
Race	Black	4268 (53%)
	Other	1219 (15%)
	White	2541 (32%)
Hispanic	No	6921 (86%)
	Unknown	768 (10%)
	Yes	339 (4%)

Table 2 Hospital outcomes and elevated liver enzyme prevalence rates

Outcome	Count (%) (95%CI)
	n = 8028
History of liver disease	245 (3.1) (2.7, 3.5)
Death	673 (8.4) (7.8, 9.0)
Hospital admission	5199 (64.8) (63.7, 65.8)
Outcome	Count (%) (95%CI)
	n = 5199
ICU admit	807 (15.5) (14.6, 16.5)
Intubation	637 (12.3) (11.4, 13.2)
Outcome	Count (%) (95%CI)
Any elevated liver enzyme	1722 (44.9) (43.3, 46.5)
Elevated AST	1297 (33.5) (32.0, 35.0)
Elevated ALT	1052 (26.7) (25.4, 28.2)
Elevated AP	392 (10.1) (9.2, 11.1)
Elevated bilirubin	468 (12.0) (11.0, 13.1)
Any super elevated liver enzyme	714 (18.6) (17.4, 19.9)
Super elevated AST	480 (12.4) (11.4, 13.5)
Super elevated ALT	468 (11.9) (10.9, 13.0)
Super elevated AP	94 (2.4) (1.9, 3.0)

ICU: Intensive care unit; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; AP: Alkaline phosphatase.