Case Report
Copyright ©The Author(s) 2021.
World J Hepatol. Jun 27, 2021; 13(6): 709-716
Published online Jun 27, 2021. doi: 10.4254/wjh.v13.i6.709
Table 1 Laboratory data on admission
Parameters
Results
Parameters
Results
WBC67 × 103/μLALP422 IU/L
Hb13.6 g/dLγ-GTP90 IU/L
Platelets32.0 × 104/μLNH3163 μg/dL
PT88.3%HBsAg(-)
TP7.3 g/dLHCVAb(+)
ALB3.6 g/dLHCV RNA(-)
T-bil1.3 mg/dLAFP30332.7 ng/mL
AST92 IU/LPIVKA-II1395 mAU/mL
ALT172 IU/L
Table 2 Hepatocellular carcinoma cases of metastasis to the brain from literature
No
Age
Sex
Presenting symptoms
Site of metastasis
Survival (from the onset of symptoms)
Ref.
125MHeadache and left weaknessRight temporoparietal brain1 dChang and Chen[5], 1979
250MWeakness of right leg, focal seizure of right legCalvarium of the skull, dura, brain3 moChang and Chen[5], 1979
351FEpistaxis, ptosis, diplopia, facial weakness in the left sideSkull base6 moChang and Chen[5], 1979
464MLoss of vision in the left eye, anorexia, weight lossLateral aspect of the temporal fossa and in the anterior portion of the middle cranial cavity3 moZubler et al[7], 1981
559MLeft arm weakness and numbness, headache with left weakness, disturbed consciousnessBrain parenchyma (right frontotemporal parietal) with intracranial haemorrhage2 moLee[8], 1992
658FProgressive enlarging scalp mass over vertex for 4 moCalvarium, dura, brain parenchyma10 moLee[8], 1992
748FProgressive enlarging scalp mass over the left parietal and right frontal region for 6 moCalvarium8 moLee[8], 1992
836MProgressive enlarging scalp mass in right occipital region for 2 moCalvarium3 moLee[8], 1992
960MDiplopia and proptosis for 2 mo. Ophthalmoplegia for 1 moSkull base (retrobulbar)7 moLee[8], 1992
1054MProgressive dysarthria and atrophy of left tongue for 2 moSkull base (jugular fossa hypoglossal canal)4 moLee[8], 1992
1147MRight hemicrania for 3 mo blurred vision with ptosis and limitation of eye movement (OD) numbness on the right forehead for one monthSkull base (parasellar)6 moLee[8], 1992
1270MLeft-sided weaknessAcute epidural hematoma adjacent to the right parietal bone2 moHayashi et al[9], 2000
1358FProgressive weakness of her right leg, right hemianesthesia and weaknessLeft parietal region, left high parietal area6 moLee and Lee[11], 1988
1450MHemiparesis and numbness of left upper arm, explosive headache and vomiting, disturbance of consciousnessRight frontotemporoparietal area2 moLee and Lee[11], 1988
1565MProgressive painful right sided proptosis and ptosis, intermittent right temporal and facial pain, loss of sensation on the right side of the faceRight orbital apex9 dPhadke and Hughes[12], 1981
1655MMild right weaknessLeft fronto-parietal cerebral hemisphere11 dPhadke and Hughes[12], 1981
1750FPtosis, diplopia, left abducens palsyClivus, cavernous sinus, petrous apexNot describedKim et al[13], 2006
1840MDiplopia, retro-orbital headache, and occasional vomitingPituitary fossa, clivus, sphenoid sinus, and right petrous apex3 moAung et al[14], 2002
1971MHeadache, diplopia, ptosis of the right eyePituitary gland, optic chiasma, cavernous sinus1 yrAung et al[14], 2002
2067MDiplopia, left retro-orbital headacheSphenoid sinus, pituitary gland, clivus15 moTamura et al[15], 2013
2158MHeadache, visual disturbance, general fatigue, diplopia, oculomotor nerve palsyPituitary fossa, cavernous sinus3 wkTamura et al[15], 2013
2273FFrontotemporal and left periorbital headache with associated photophobiaLeft sphenoid sinus, cavernous sinusNot describedMorais et al[16], 2018
2382FHyperalgesia of the right face and limited abduction of the right eyeCavernous sinus, Meckel's cave, petrous bone5.5 moOur case