Prospective Study
Copyright ©The Author(s) 2021.
World J Hepatol. Dec 27, 2021; 13(12): 2168-2178
Published online Dec 27, 2021. doi: 10.4254/wjh.v13.i12.2168
Table 1 Summary of the patient population

Overall (n = 23)
Age (median, IQR), n (%)60
Male1460.9
Caucasian1565%
Etiology of cirrhosis
Alcohol (EtOH)313.0
Granulomatous hepatitis14.4
HBV14.4
HCV1043.5
HCV, EtOH14.4
Nonalcoholic steatohepatitis626.1
Primary sclerosing cholangitis14.4
Liver biopsy1043.5
Liver transplantation313.0
Portal hypertension on imaging1773.9
TIPS28.7
Cirrhosis on CT/US23100.0
History of connective tissue disease14.4
Dialysis28.7
Endoscopy suite, n (%)
Reason for EGD
Anemia14.4
GI Bleed417.4
Varices1878.2
Anticoagulation00.0
Alcohol use in the past 15 d521.7
ASA in the past 15 d731.8
NSAIDS use in the past 15 d00.0
Plavix00.0
Beta blockers1045.5
Labs within 3 mo Pre EGD1medianIQR
Hemoglobin10.69.5–13.3
Mean corpuscular volume89.287.0–90.5
Platelet count126.568.0–152.0
INR1.11.1–1.2
Serum sodium139.0137.0–142.0
Alanine aminotransferase30.025.0–54.0
Aspartate aminotransferase50.032.0–79.0
Total bilirubin1.61.2–2.6
Alkaline phosphatase108.085.0–134.0
Serum albumin3.22.4–3.4
Ferritin74.35.0–2458.0
Creatinine1.00.70–1.47
Labs within 4-8 wk after EGD1medianIQR
Hemoglobin11.48.9–12.8
Mean corpuscular volume87.984.8–91.6
Platelet count117.063.0–166.0
INR1.21.1–1.3
Serum sodium140.0137.0–142.0
Alanine aminotransferase31.021.0–42.0
Aspartate aminotransferase44.029.0–68.0
Total bilirubin1.20.9–1.9
Alkaline phosphatase132.079.0–185.0
Serum albumin3.02.6–3.3
Ferritin197.463.0–199.0
Creatinine1.00.70–1.50
Table 2 Comparison of white light and I-scan to the gold standard biopsy for diagnosis of gastric antral vascular ectasia


Biopsy

No GAVEGAVE
White LightNo GAVE101Sensitivity: 85.7%
GAVE66Specificity: 62.5%
I-ScanNo GAVE120Sensitivity: 100%
GAVE47Specificity: 75.0%
Table 3 Comparison of white light and I-scan to the gold standard biopsy for diagnosis of portal hypertensive gastropathy


Biopsy

No PHGPHG
White LightNo PHG41Sensitivity: 93.8%
PHG315Specificity: 57.1%
I-ScanNo PHG52Sensitivity: 87.5%
PHG214Specificity: 71.4%