Percutaneous microwave ablation vs radiofrequency ablation in the treatment of hepatocellular carcinoma

Table 2 Comparison of clinical outcomes across published series of hepatocellular carcinoma patients for microwave ablation over radiofrequency

Ref.	Method	Guidance	Patients	Lesions	Mean age	Time	Size in cm	Complete	Local recurrence (%)	Overall survival
								ablation (%)		1 yr (%)	2 yr (%)	3 yr (%)	4 yr (%)	5 yr (%)	Median (mo)
Shibata et al[50]	MWA	Percutaneous	36	46	62.5	-	< 4	89	17.4	-	-	-	-	-	-
	RFA	Percutaneous	36	48	63.6	-	< 4	96	8.3	-	-	-	-	-	-
Xu et al[84]	MWA	Percutaneous	54	112	53.4	-	2.5 ± 1.1	94.6	7.1	-	-	-	-	-	-
	RFA	Percutaneous	43	78	53.4	-	2.6 ± 1.4	89.7	12.8	-	-	-	-	-	-
Simo et al[85]	MWA	Laparoscopic, US	13	15	59	8-10 min	2.31	-	-	-	-	-	-	-	7
	RFA	Laparoscopic, US	22	27	59	10-12 min	2.53	-	-	-	-	-	-	-	19
Lu et al[78]	MWA	Percutaneous, US	49	98	50.1	5 min	3 (25/49)	94.9	11.8	81.6	61.2	50.5	36.8	-	32.5
	RFA	Percutaneous, US	53	72	54.5	10 min	3 (32/53)	93.1	20.9	71.7	47.2	37.6	24.2		27.1
Qian et al[63]	MWA	Percutaneous, US	22	22	52	-	4.8	95.5	18	-	-	-	-	-	-
	RFA	Percutaneous, US	20	20	56	-	3.5	95	15	-	-	-	-	-	-
Zhang et al[86]	MWA	Percutaneous, US	77	105	54	8 min	< 3 (36), 3.1 to 5 (41)	86.7	10.5	92.2	-	51.7	-	38.5	-
	RFA	Percutaneous, US	78	97	54	6-20 min	< 3 (47), 3.1 to 5 (31)	83.4	11.8	91	-	64.1	-	41.3	-
Abdelaziz et al[79]	MWA	Percutaneous	66	-	53.5	-	2.9 ± 0.97	96.1	3.9	96.4	62	-	-	-	-
	RFA	Percutaneous	45	-	56.8	-	2.95 ± 1.03	94.2	13.5	67.6	47.4	-	-	-	-
Ding et al[81]	MWA	Percutaneous	85	98	59	10	< 3	98.5	10.9	98.7	92.3	82.7	77.8	-	45.34
	RFA	Percutaneous	113	131	58.6	12	< 3	99	5.2	98	90.7	77.6	77.6	-	52.99
Ohmoto et al[80]	MWA	Percutaneous	49	56	64		< 2		19	89	70	49	39	-	-
	RFA	Percutaneous	34	37	67		< 2		9	100	83	70	70	-	-

MWA: Microwave ablation; RFA: Radiofrequency; US: Ultrasonography.