Copyright ©The Author(s) 2015.
World J Hepatol. Jul 8, 2015; 7(13): 1730-1734
Published online Jul 8, 2015. doi: 10.4254/wjh.v7.i13.1730
Figure 1
Figure 1 Theoretically ideal therapies against cirrhosis-related thrombocytopenia depending on the etiology. The platelet count in cirrhotics is determined mainly by three major factors, including (A) a rate of thrombopoiesis, (B) the presence/abscence of hypersplenism, and (C) the presence/abscence of thrombotic diathesis, which differently affect each case. Patients with thrombocytopenic conditions A, B, or C are considered to respond well to thrombopoietin receptor agonists, splenectomy, and anti-platelet/coagulation drugs, respectively. In patients with condition D, a combination of thrombopoietin receptor agonists and anti-platelet/coagulation drugs is thought to be necessary.