Copyright ©2014 Baishideng Publishing Group Co.
World J Hepatol. Apr 27, 2014; 6(4): 217-225
Published online Apr 27, 2014. doi: 10.4254/wjh.v6.i4.217
Figure 1
Figure 1 Risk factors for non-alcoholic fatty liver disease development. In this figure, all risk factors for non-alcoholic fatty liver disease (NAFLD) are summarized. We divided the risk factors in modifiable and not modifiable. Among not modifiable risk factors we listed PNPLA3 rs738409, but as underlined in the text, the weight loss can modify the capacity of PNPLA3 polymorphism to lead to hepatic steatosis. PNPLA3: Patatin like phospholipase 3 gene; GCKR: Glucokinase regulatory protein; FDFT1: Farnesyl-diphosphate farnesyltransferase 1; NCAN: Neurocan; PPP1R3B: Protein phosphatase 1 regulatory subunit 3B; LYPLAL1: Lysophospholipase-like 1; GC: Group-specific component; LCP1: Lymphocyte cytosolic protein-1; LPPR4: Lipid phosphate phosphatise-related protein type 4; SLC38A8: Solute carrier family 38 member 8; APOC3: Apolipoprotein C3 gene; SAMM50: Sorting and assembly machinery component; PARVB: Parvin beta.