Copyright ©2014 Baishideng Publishing Group Co.
World J Hepatol. Jan 27, 2014; 6(1): 41-54
Published online Jan 27, 2014. doi: 10.4254/wjh.v6.i1.41
Table 1 Proposal for diagnostic and supportive criteria for cirrhotic cardiomyopathy agreed upon at a working party held at the 2005 World Congress of Gastroenterology
A working definition of cirrhotic cardiomyopathy
A cardiac dysfunction in patients with cirrhosis characterised by impaired contractile responsiveness to stress and/or altered diastolic relaxation with electrophysiological abnormalities in the absence of other known cardiac disease
Diagnostic criteria
Systolic dysfunction
Blunted increase in cardiac output with exercise, volume challenge or pharmacological stimuli
Resting EF < 55%
Diastolic dysfunction
E/A ratio < 1.0 (age-corrected)
Prolonged deceleration time (> 200 ms)
Prolonged isovolumetric relaxation time (> 80 ms)
Supportive criteria
Electrophysiological abnormalities
Abnormal chronotropic response
Electromechanical uncoupling/dyssynchrony
Prolonged QTc interval
Enlarged left atrium
Increased myocardial mass
Increased BNP and pro-BNP
Increased troponin I