Ciclosporin does not attenuate intracranial hypertension in rats with acute hyperammonaemia

Table 3 Biochemistry at t = 4 h

Group	ALT (U/L)	Arterial ammonia (μmol/L)	PP (arb. units)
PCA + ammonia infusion + Cs	525 ± 185	1165.5 ± 87.2	0.32 ± 0.01
PCA + ammonia infusion + vehicle	600 ± 266	900.5 ± 70	0.37 ± 0.02
PCA + saline infusion + Cs	470 ± 221	108.3 ± 5.9	0.40 ± 0.03
PCA + saline infusion + vehicle	830 ± 468	140.3 ± 15	0.33 ± 0.03

PCA: Portacaval anastomosis; Cs: Ciclosporin; ALT: Alanine transferase; PP: Coagulation factor II + VII + X.