Indocyanine green kinetics to assess liver function: Ready for a clinical dynamic assessment in major liver surgery?

Figure 1 Liver function assessment: Static and dynamic tests (modified from Sakka[3], 2007). AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; ICG: Indocyanine green; GGT: Gamma glutamyl transferase.

Figure 2 Indocyanine green dilution curve. A: First peak; B: Second peak (re-circulation phase); C: Elimination phase (Modified from Vos et al[6], 2014). ICG: Indocyanine green; C_ICG: ICG blood concentration.

Figure 3 Schematic representation of indocyanine green kinetics (modified from Imamura et al[5], 2005).

Figure 4 Makuuchi decisional algorithm to select liver resective procedures in cirrhotic patients according to liver functional reserve (from Imamura et al[5], 2005). ICG_R15: Indocyanine green retention ratio at 15 min.