Role of pentoxifylline in non-alcoholic fatty liver disease in high-fat diet-induced obesity in mice

Figure 1 Pentoxifylline effects on non-alcoholic fatty liver disease in mice. A: Liver of lean mice and pentoxifylline-treated lean mice; B: A normal histology; C: Liver of mice on a high-fat diet for 12 wk; D: Treated with pentoxifylline shows pronounced steatosis. Hematoxylin-eosin staining of 4.0 μm sections of livers. Magnification: 200 ×; E: Hepatic triglycerides content was determined and expressed as mg/mg of liver tissue of all groups. Data are shown as mean ± SEM of 4 mice per group, ^aP = 0.07. NT: Non-treated; PTX: Pentoxifylline; HFD: High-fat diet.