Original Article
Copyright ©2014 Baishideng Publishing Group Co.
World J Hepatol. Feb 27, 2014; 6(2): 72-84
Published online Feb 27, 2014. doi: 10.4254/wjh.v6.i2.72
Figure 1
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Figure 1 Survival curves. OLT: Orthotopic liver transplantation; SOLT: Split orthotopic liver transplantation.
Figure 2
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Figure 2 Histopathological and immunohistological assessments. A: Liver damage score in HE staining; B: TUNEL-positive rate; C: Caspase-3-positive rate. aP < 0.05 vs control. OLT: Orthotopic liver transplantation; SOLT: Split orthotopic liver transplantation.
Figure 3
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Figure 3 Biochemical and coagulation profiles. A: Serum aspartate aminotransferase (AST); B: Serum alanine aminotransferase (ALT); C: Serum total bilirubin (T-Bil); D: Plasma international normalized ratio of prothrombin time (PT-INR); E: Serum hyaluronic acid (HA). aP < 0.05 vs control. NS: Not significant (P≥ 0.05); OLT: Orthotopic liver transplantation; SOLT: Split orthotopic liver transplantation.
Figure 4
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Figure 4 Protein expression of malondialdehyde, 4-hydroxynonenal, ataxia-telangiectasia mutated kinas/H2AX, phosphatidylinositol 3-kinase/Akt and antioxidant enzymes. A: Actual intensities of malondialdehyde (MDA) in western blotting; B: Normalized MDA; C: Normalized 4-hydroxynonenal (4-HNE); D: Normalized ataxia-telangiectasia mutated kinase (ATM); E: Normalized γH2AX; F: Actual intensities of phosphatidylinositol 3-kinase (PI3K) and Akt in western blotting; G: Normalized PI3K; H: Normalized Akt; I: Normalized superoxide dismutase (SOD); J: Normalized catalase. aP < 0.05 vs control. NS: Not significant (P≥ 0.05); OLT: Orthotopic liver transplantation; SOLT: Split orthotopic liver transplantation.
Figure 5
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Figure 5 Protein expression and activities of matrix metalloproteinases and tissue inhibitor of metalloproteinases. A: Actual protein expression and activities of matrix metalloproteinase (MMP)-9; B: Normalized MMP-9; C: Normalized MMP-2; D: Normalized tissue inhibitor of metalloproteinase (TIMP)-1; E: Normalized TIMP-2; F: Relative MMP-9; G: Relative MMP-2; H: Relative TIMP-1; I: Relative TIMP-2. aP < 0.05 vs control. NS: Not significant (P≥ 0.05); OLT: Orthotopic liver transplantation; SOLT: Split orthotopic liver transplantation.