From virological selection to immune stratification: Hepatitis B virus-specific T cells for precision pegylated interferon therapy in chronic hepatitis B

doi:10.4254/wjh.124884

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Hepatol. Sep 27, 2026; 18(9): 124884
Published online Sep 27, 2026. doi: 10.4254/wjh.124884

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Figure 1 Conceptual framework of hepatitis B virus-specific T cell-guided immune stratification for precision pegylated interferon therapy in chronic hepatitis B. HBV: Hepatitis B virus; PEG-IFN: Pegylated interferon; IFN-γ: Interferon-γ; TNF-α: Tumor necrosis factor-α; IL: Interleukin; NAD: Nicotinamide adenine dinucleotide; HBsAg: Hepatitis B surface antigen; HBcrAg: Hepatitis B core-related antigen.

Citation: Tian B, Tian C, Shen CL, Zhang Q. From virological selection to immune stratification: Hepatitis B virus-specific T cells for precision pegylated interferon therapy in chronic hepatitis B. World J Hepatol 2026; 18(9): 124884
URL: https://www.wjgnet.com/1948-5182/full/v18/i9/124884.htm
DOI: https://dx.doi.org/10.4254/wjh.124884

Tian B, Tian C, Shen CL, Zhang Q. From virological selection to immune stratification: Hepatitis B virus-specific T cells for precision pegylated interferon therapy in chronic hepatitis B. World J Hepatol 2026; 18(9): 124884 [DOI: 10.4254/wjh.124884]

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