Validation of genetic variants associated with metabolic dysfunction-associated fatty liver disease in an ethnic Chinese population

Figure 1 Single nucleotide polymorphisms in patients with or without metabolic dysfunction-associated fatty liver disease. The bar charts represent the percent of each allele comparing metabolic dysfunction-associated fatty liver disease (MAFLD) patients (blue) and controls (green). ¹Chi-squared test; ²Fisher’s exact test.

Figure 2 Area under curve of the regression model including PNPLA3 GG. Area under curve by receiver operating characteristic is 0.823 (95% confidence interval: 0.73-0.91, P < 0.001). Regression equation -7.01+0.849 (triglycerides) + 0.218 (body mass index) + 1.422 (PNPLA3 GG). Positive predictive value = 72.1%. Negative predictive value = 65.4%.