Complements are involved in alcoholic fatty liver disease, hepatitis and fibrosis

Figure 1 Complement activation pathway and regulation. Three pathways (classical, pathway, mannan-binding lectin, and alternative) are involved in complement activation. Green arrows without a red line indicate the process of complement activation. Green arrows with red line indicate the the process of inhibiting complement activation. MBL: Mannan-binding lectin; MASP: MBL-associated proteases; FB: Factor B; FH: Factor H; FI: Factor I.