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World J Hepatol. Apr 27, 2013; 5(4): 160-169
Published online Apr 27, 2013. doi: 10.4254/wjh.v5.i4.160
Published online Apr 27, 2013. doi: 10.4254/wjh.v5.i4.160
Melatonin attenuates high fat diet-induced fatty liver disease in rats
Gregorios Hatzis, Panayiotis Ziakas, Stamatios Chatzis, Department of Pathophysiology, Athens University School of Medicine, 11527 Athens, Greece
Nikolaos Kavantzas, Department of Pathology, Athens University School of Medicine, 11527 Athens, Greece
Aggeliki Triantafyllou, Department of Biological Chemistry, Athens University School of Medicine, 11527 Athens, Greece
Panagiotis Sigalas, Ioanna Andreadou, Konstantinos Ioannidis, Department of Pharmaceutical Chemistry, Athens University School of Pharmacy, Panepistimiopolis of Zographou, Zografou, 15771 Athens, Greece
Konstantinos Filis, Fragiska Sigala, 1st Department of Propaedeutic Surgery, Athens University School of Medicine, 11527 Athens, Greece
Alexandros Papalampros, 1st Department of Surgery, Athens University School of Medicine, 11527 Athens, Greece
Author contributions: All authors contributed to the scientific acquisition of data and the writing of the final version of the manuscript; Hatzis G conceived of the study, devised its experimental design, coordinated the study, interpret the data, and was a major contributor in the writing of the manuscript; Ziakas P did the statistical analysis and contributed to the interpretation of the data; Kavantzas N did histopathological examinations of the tissue biopsies; Triantafyllou A performed the biochemical tests and the malondialdehyde and glutathione assays; Sigalas P was responsible for the welfare of the animals and the collection and storage of tissues and sera; Andreadou I performed the biochemical tests and the malondialdehyde and glutathione assays; Ioannidis K was responsible for the welfare of the animals and the collection and storage of tissues and sera; Chatzis S was a contributor in writing and revising the manuscript; Filis K was responsible for the welfare of the animals and the collection and storage of tissues and sera; Papalampros A performed invasive procedures on the animals; Sigala F contributed to the conception of the study, performed the invasive procedures, and oversaw the welfare of the animals as well as the collection and storage of tissues and sera.
Supported by Grant from the Special Account for Research Funds (ELKE) of the National and Kapodistrian University of Athens, Greece, ref. 7493
Correspondence to: Dr. Gregorios Hatzis, Associate Professor of Pathophysiology, Department of Pathophysiology, Athens University School of Medicine, 75 Mikras Asias, 11527 Athens, Greece. grhatzis@med.uoa.gr
Telephone: +30-210-7462674 Fax: +30-210-7462664
Received: October 27, 2012
Revised: December 13, 2012
Accepted: January 17, 2013
Published online: April 27, 2013
Revised: December 13, 2012
Accepted: January 17, 2013
Published online: April 27, 2013
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