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Ozkan SG, Avci S, Urusak A, Buyukyatikci AA, Ali K, Safaei S, Altuntas Y, Ozturkmen YA, Durak ZA, Yildiz MS, Ozkan HA. Which Nutritional Scoring System Best Predicts Transplant Outcomes in Allogeneic Stem Cell Recipients? A Comparison of Nutritional Risk Index, Prognostic Nutritional Index, and Controlling Nutritional Status. SISLI ETFAL HASTANESI TIP BULTENI 2025; 59:64-75. [PMID: 40226570 PMCID: PMC11983031 DOI: 10.14744/semb.2025.74050] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Subscribe] [Scholar Register] [Received: 12/25/2024] [Revised: 02/06/2025] [Accepted: 02/10/2025] [Indexed: 04/15/2025]
Abstract
Objectives Nutritional status significantly impacts outcomes in allogeneic hematopoietic stem cell transplantation (allo-HSCT). Among various indices, the Nutritional Risk Index (NRI), Prognostic Nutritional Index (PNI), and Controlling Nutritional Status (CONUT) scores hold potential as prognostic tools. This study compares their predictive utility for transplant outcomes. Methods A retrospective analysis was conducted on 41 patients who underwent their first allo-HSCT between October 2022 and July 2024. Nutritional scores were calculated using pre-transplant data, and their associations with mortality and non-relapse mortality (NRM) were assessed. Receiver operating characteristic (ROC) curves and multivariable logistic regression were employed to evaluate predictive accuracy. Results The high CONUT score demonstrated the highest prognostic accuracy for mortality (AUC: 0.771, p=0.026) and NRM (AUC: 0.806, p=0.047). It was the sole independent predictor of mortality (OR: 2.180, p=0.028). Both the NRI (AUC: 0.737, p=0.040) and PNI (AUC: 0.803, p=0.008) were also associated with mortality but lacked independent predictive value. Higher CONUT scores correlated with increased mortality rates. Conclusion The CONUT score emerged as the most effective nutritional scoring system for predicting mortality in allo-HSCT patients. Its simplicity and integration of key clinical parameters make it a valuable tool for early risk stratification and targeted interventions. Further studies with larger cohorts are warranted to validate these findings and refine nutritional management strategies.
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Affiliation(s)
- Sidika Gulkan Ozkan
- Division of Hematology, Department of Internal Medicine, Bahcesehir University Faculty of Medicine, Istanbul, Türkiye
| | - Suna Avci
- Department of Geriatric Medicine, Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine, Istanbul, Türkiye
| | - Ada Urusak
- University of Health Sciences Türkiye, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye
| | - Arif Ataberk Buyukyatikci
- University of Health Sciences Türkiye, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Türkiye
| | - Kimiaei Ali
- Division of Hematology, Department of Internal Medicine, Bahcesehir University Faculty of Medicine, Istanbul, Türkiye
| | - Seyedehtina Safaei
- Division of Hematology, Department of Internal Medicine, Bahcesehir University Faculty of Medicine, Istanbul, Türkiye
| | - Yuksel Altuntas
- Division of Endocrinology, Department of Internal Medicine, University of Health Sciences Türkiye, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye
| | - Yuksel Asli Ozturkmen
- Division of Hematology, Department of Internal Medicine, Sivas Numune Hospital, Sivas, Türkiye
| | - Zeynep Asli Durak
- Division of Hematology, Department of Internal Medicine, Bahcesehir University Faculty of Medicine, Istanbul, Türkiye
| | - Mehmet Serdar Yildiz
- Department of Internal Medicine, University of Health Sciences Türkiye, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye
| | - Hasan Atilla Ozkan
- Division of Hematology, Department of Internal Medicine, Bahcesehir University Faculty of Medicine, Istanbul, Türkiye
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Gogas Yavuz D, Akhtar O, Low K, Gras A, Gurser B, Yilmaz ES, Basse A. The Economic Impact of Obesity in Turkey: A Micro-Costing Analysis. CLINICOECONOMICS AND OUTCOMES RESEARCH 2024; 16:123-132. [PMID: 38476579 PMCID: PMC10929251 DOI: 10.2147/ceor.s446560] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/17/2023] [Accepted: 02/28/2024] [Indexed: 03/14/2024] Open
Abstract
Background Turkey currently has the highest obesity prevalence among its European counterparts. 32% and 61% of the population live with obesity and overweight, respectively. Overweight and obesity are linked to non-communicable diseases that incur incremental health and economic costs. The significant public health concern warrants an assessment of the cost of obesity. Methods A micro-costing approach from the public payer perspective was conducted to estimate direct healthcare costs associated with ten obesity-related comorbidities (ORCs) in Turkey. Clinical practice guidelines and a systematic literature review informed ORCs and the respective cost categories. This was subsequently validated by a steering committee comprising seven experts. Seventy public sector physicians were surveyed to estimate healthcare resource use. Unit costs were derived from Social Security Institute's Healthcare Implementation Communique. Cost items were summed to determine the annual cost per patient per ORC, which was validated by the steering committee. Medical inflation was considered in a scenario analysis that varied resource unit costs. Results Chronic kidney disease, heart failure and type 2 diabetes are the costliest ORCs, incurring an annual cost of 28,600 TRY, 16,639 TRY and 11,993 TRY, respectively. Individuals in Turkey with any ORC triggered direct healthcare costs ranging 1857-28,600 TRY annually. Costs were driven by tertiary care resources arising from treatment-related adverse events, disease complications and inpatient procedures. In the scenario analysis, medical resource unit costs were inflated by 18.7% and 39.4%, triggering an average increase in cost across all ORCs of 1998 TRY and 4210 TRY, respectively. Conclusion Our findings confirm that obesity and its complications result in significant financial burden to the public healthcare system. By quantifying the burden of obesity across a comprehensive spectrum of ORCs, our study aims to support the economic case for investing in appropriate obesity interventions.
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Affiliation(s)
- Dilek Gogas Yavuz
- School of Medicine, Marmara University, Section of Endocrinology and Metabolism, Istanbul, Turkey
| | | | - Kaywei Low
- Healthcare Market Access, Ipsos, Singapore
| | | | | | | | - Amaury Basse
- Novo Nordisk, Novo Nordisk Region South East Europe, Middle East & Africa, Zurich, Switzerland
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Babayigit M, Dogan E, Babayigit MA, Bulus H, Sahin M, Ozayar E. Response to the Letter of Dr Somoza et al. J Perianesth Nurs 2022; 37:582. [PMID: 36182243 DOI: 10.1016/j.jopan.2022.07.003] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/27/2022] [Accepted: 07/12/2022] [Indexed: 10/14/2022]
Affiliation(s)
- Munire Babayigit
- Ataturk Sanatorium Training and Research Hospital, Department of Anesthesiology and Reanimation, Ankara, Turkey.
| | - Esra Dogan
- Ataturk Sanatorium Training and Research Hospital, Department of Anesthesiology and Reanimation, Ankara, Turkey
| | | | - Hakan Bulus
- Ataturk Sanatorium Training and Research Hospital, Department of General Surgery, Ankara, Turkey
| | - Mutlu Sahin
- Koru Hospital, Department of General Surgery, Ankara, Turkey
| | - Esra Ozayar
- Ataturk Sanatorium Training and Research Hospital, Department of Anesthesiology and Reanimation, Ankara, Turkey
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Karaman O, Alhudhaif A, Polat K. Development of smart camera systems based on artificial intelligence network for social distance detection to fight against COVID-19. Appl Soft Comput 2021; 110:107610. [PMID: 36569211 PMCID: PMC9760412 DOI: 10.1016/j.asoc.2021.107610] [Citation(s) in RCA: 13] [Impact Index Per Article: 3.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/27/2021] [Revised: 05/17/2021] [Accepted: 06/14/2021] [Indexed: 12/27/2022]
Abstract
In this work, an artificial intelligence network-based smart camera system prototype, which tracks social distance using a bird's-eye perspective, has been developed. "MobileNet SSD-v3", "Faster-R-CNN Inception-v2", "Faster-R-CNN ResNet-50" models have been utilized to identify people in video sequences. The final prototype based on the Faster R-CNN model is an integrated embedded system that detects social distance with the camera. The software developed using the "Nvidia Jetson Nano" development kit and Raspberry Pi camera module calculates all necessary actions in itself, detects social distance violations, makes audible and light warnings, and reports the results to the server. It is predicted that the developed smart camera prototype can be integrated into public spaces within the "sustainable smart cities," the scope that the world is on the verge of a change.
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Affiliation(s)
- Onur Karaman
- Akdeniz University, Vocational School of Health Services, Department of Medical Imaging Techniques, Antalya, 07070, Turkey
| | - Adi Alhudhaif
- Department of Computer Science, College of Computer Engineering and Sciences in Al-kharj, Prince Sattam bin Abdulaziz University, P.O. Box 151, Al-Kharj 11942, Saudi Arabia
| | - Kemal Polat
- Department of Electrical and Electronics Engineering, Bolu Abant Izzet Baysal University, Bolu, Turkey,Correspondence to: Bolu Abant Izzet Baysal University, Faculty of Engineering, Department of Electrical and Electronics Engineering, Bolu, Turkey
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Sezgin O, Akpınar H, Özer B, Törüner M, Bal K, Bor S. Population-based assessment of gastrointestinal symptoms and diseases: Cappadocia Cohort, Turkey. TURKISH JOURNAL OF GASTROENTEROLOGY 2020; 30:1009-1020. [PMID: 31854305 DOI: 10.5152/tjg.2019.19882] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.4] [Reference Citation Analysis] [Abstract] [Track Full Text] [Subscribe] [Scholar Register] [Indexed: 12/15/2022]
Abstract
BACKGROUND/AIMS The aim of this study was to determine the prevalence of symptoms and diseases of the lower and upper gastrointestinal system (GIS) in a population-based sample. MATERIALS AND METHODS The cross-sectional cohort study was conducted in Cappadocia cohort comprising the Gülşehir and Avanos districts. The "Gastrointestinal Symptom Questionnaire" was applied to persons over the age of 18 years. RESULTS The GI Symptom Questionnaire was applied to 3369 subjects, and height and body weight were measured in 2797 consenting subjects. Of the participants, 61% were female and the mean patient age was 50±15 years. At least one GI symptom was present in 70.6% of the cohort. The most common upper GI symptoms were gastric bloating (31.0%) and heartburn (29.1%). The most common lower GI symptom was abnormal defecation (33.5). The prevalence of upper GIS and lower GIS diseases was 32.7% and 12.9%, respectively, and the prevalence of togetherness of upper and lower GIS diseases was 9.9%. Prevalence of GIS disease was approximately 3 times higher in females (p<0.001). All of the upper and lower GI symptoms and the prevalence of upper GIS disease increased in line with Body mass index (BMI). CONCLUSION This first population-based, cross-sectional cohort study revealed that the prevalence of GIS diseases is critically high for optimal public health. Special attention must be paid to these diseases while planning health policies and reimbursements.
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Affiliation(s)
- Orhan Sezgin
- Department of Gastroenterology, Mersin University School of Medicine, Mersin, Turkey
| | - Hale Akpınar
- Department of Gastroenterology, Dokuz Eylül University School of Medicine, İzmir, Turkey
| | - Birol Özer
- Department of Gastroenterology, Başkent University School of Medicine, Ankara, Turkey
| | - Murat Törüner
- Department of Gastroenterology, Ankara University School of Medicine, Ankara, Turkey
| | - Kadir Bal
- Department of Gastroenterology, İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa School of Medicine, İstanbul, Turkey
| | - Serhat Bor
- Department of Gastroenterology, Ege University School of Medicine, İzmir, Turkey
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Islek D, Demiral Y, Ergor G, Unal B. Quantifying gender inequalities in obesity: findings from the Turkish population-based Balcova Heart Study. Public Health 2020; 186:265-270. [PMID: 32871448 DOI: 10.1016/j.puhe.2020.06.044] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.2] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/29/2020] [Revised: 06/12/2020] [Accepted: 06/17/2020] [Indexed: 10/23/2022]
Abstract
OBJECTIVES Sparse evidence is available to explain obesity variations between genders in the Turkish population. To our knowledge, no previous study has analysed the magnitude of gender differences in obesity using common social determinants of health. We aimed to quantify gender inequalities in obesity in terms of education, employment status, occupation and perceived income in a Turkish population. STUDY DESIGN The study design used is a cross-sectional study. METHODS Population-based data from the Balcova Heart Study (n = 16,080) were analysed. Logistic regression models were used to calculate the crude and adjusted odds ratios (ORs) when comparing obesity prevalence in women vs men within each category of social determinants. RESULTS Women had a higher risk of being obese than men (adjusted OR [aOR] = 2.04 [95% confidence interval {CI}: 1.7-2.1]). Gender inequality in obesity decreased as the level of education increased, from 'primary school' (aOR = 2.5 [95% CI: 2.2-2.8]) to 'university' (aOR = 0.9 [95% CI: 0.6-1.1]). Women had a higher risk of obesity within the 'unemployed' category compared with men (aOR = 2.2 [95% CI: 1.6-3.0]). Gender inequality in obesity decreased with a higher perception of income, from 'low' (aOR = 2.1 [95% CI: 1.6-3.0]) to 'high' (aOR = 1.5 [95% CI: 1.2-2.0]). CONCLUSIONS These findings highlight the fact that gender inequalities in obesity are greatest within populations of low education, unemployment and lower perception of income. Reduced gender inequality in obesity prevalence was seen for the subpopulation with professional occupations, with women having decreased odds of obesity compared with men. Conversely, unemployed women had increased odds of obesity compared with unemployed men. Increasing the status of women should be prioritised in policies to tackle obesity in the Turkish population and in similar developing populations elsewhere.
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Affiliation(s)
- D Islek
- Emory University, Rollins School of Public Health, Department of Epidemiology, Atlanta, USA.
| | - Y Demiral
- Dokuz Eylul University Faculty of Medicine, Department of Public Health, Izmir, Turkey.
| | - G Ergor
- Dokuz Eylul University Faculty of Medicine, Department of Public Health, Izmir, Turkey.
| | - B Unal
- Dokuz Eylul University Faculty of Medicine, Department of Public Health, Izmir, Turkey.
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Increased prevalence of portal vein thrombosis in patients with nonalcoholic steatohepatitis-cirrhosis due to increased proinflammatory cytokines releasing from abdominal adipose tissue. Eur J Gastroenterol Hepatol 2020; 32:458. [PMID: 32011389 DOI: 10.1097/meg.0000000000001564] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.2] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 12/10/2022]
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Engel NW, Schliffke S, Schüller U, Frenzel C, Bokemeyer C, Kubisch C, Lessel D. Fatal Myelotoxicity Following Palliative Chemotherapy With Cisplatin and Gemcitabine in a Patient With Stage IV Cholangiocarcinoma Linked to Post Mortem Diagnosis of Fanconi Anemia. Front Oncol 2019; 9:420. [PMID: 31192125 PMCID: PMC6540739 DOI: 10.3389/fonc.2019.00420] [Citation(s) in RCA: 11] [Impact Index Per Article: 1.8] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/04/2019] [Accepted: 05/03/2019] [Indexed: 12/16/2022] Open
Abstract
Unrecognized genome instability syndromes can potentially impede the rational treatment of cancer in rare patients. Identification of cancer patients with a hereditary condition is a compelling necessity for oncologists, giving varying hypersensitivities to various chemotherapeutic agents or radiation, depending on the underlying genetic cause. Omission of genetic testing in the setting of an overlooked hereditary syndrome may lead to unexpected and unbearable toxicity from oncological standard approaches. We present a case of a 33-year-old man with an early-onset stage IV intrahepatic cholangiocarcinoma, who experienced unusual bone marrow failure and neutropenic fever syndrome as a consequence of palliative chemotherapy containing cisplatin and gemcitabine, leading to a fatal outcome on day 25 of his first chemotherapeutic cycle. The constellation of bone marrow failure after exposure to the platinum-based agent cisplatin, the presence of an early-onset solid malignancy and the critical appraisal of further phenotypical features raised suspicion of a hereditary genome instability syndrome. Whole-exome sequencing from buccal swab DNA enabled the post mortem diagnosis of Fanconi anemia, most likely linked to the fatal outcome due to utilization of the DNA crosslinking agent cisplatin. The patient's phenotype was exceptional, as he never displayed significant hematologic abnormalities, which is the hallmark of Fanconi anemia. As such, this case stresses the importance to at least question the possibility of a hereditary basis in cases of relatively early-onset malignancy before defining an oncological treatment strategy.
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Affiliation(s)
- Nils W Engel
- Department of Oncology, Haematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald Tumorzentrum, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
| | - Simon Schliffke
- Department of Oncology, Haematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald Tumorzentrum, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
| | - Ulrich Schüller
- Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.,Department of Pediatric Hematology and Oncology, University Medical Center, Hamburg-Eppendorf, Germany.,Research Institute Children's Cancer Center Hamburg, Hamburg, Germany
| | - Christian Frenzel
- Department of Oncology, Haematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald Tumorzentrum, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
| | - Carsten Bokemeyer
- Department of Oncology, Haematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald Tumorzentrum, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
| | - Christian Kubisch
- Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
| | - Davor Lessel
- Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
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Jaacks LM, Vandevijvere S, Pan A, McGowan CJ, Wallace C, Imamura F, Mozaffarian D, Swinburn B, Ezzati M. The obesity transition: stages of the global epidemic. Lancet Diabetes Endocrinol 2019; 7:231-240. [PMID: 30704950 PMCID: PMC7360432 DOI: 10.1016/s2213-8587(19)30026-9] [Citation(s) in RCA: 718] [Impact Index Per Article: 119.7] [Reference Citation Analysis] [Abstract] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 12/04/2018] [Revised: 01/06/2019] [Accepted: 01/07/2019] [Indexed: 02/06/2023]
Abstract
The global prevalence of obesity has increased substantially over the past 40 years, from less than 1% in 1975, to 6-8% in 2016, among girls and boys, and from 3% to 11% among men and from 6% to 15% among women over the same time period. Our aim was to consolidate the evidence on the epidemiology of obesity into a conceptual model of the so-called obesity transition. We used illustrative examples from the 30 most populous countries, representing 77·5% of the world's population to propose a four stage model. Stage 1 of the obesity transition is characterised by a higher prevalence of obesity in women than in men, in those with higher socioeconomic status than in those with lower socioeconomic status, and in adults than in children. Many countries in south Asia and sub-Saharan Africa are presently in this stage. In countries in stage 2 of the transition, there has been a large increase in the prevalence among adults, a smaller increase among children, and a narrowing of the gap between sexes and in socioeconomic differences among women. Many Latin American and Middle Eastern countries are presently at this stage. High-income east Asian countries are also at this stage, albeit with a much lower prevalence of obesity. In stage 3 of the transition, the prevalence of obesity among those with lower socioeconomic status surpasses that of those with higher socioeconomic status, and plateaus in prevalence can be observed in women with high socioeconomic status and in children. Most European countries are presently at this stage. There are too few signs of countries entering into the proposed fourth stage of the transition, during which obesity prevalence declines, to establish demographic patterns. This conceptual model is intended to provide guidance to researchers and policy makers in identifying the current stage of the obesity transition in a population, anticipating subpopulations that will develop obesity in the future, and enacting proactive measures to attenuate the transition, taking into consideration local contextual factors.
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Affiliation(s)
- Lindsay M Jaacks
- Department of Global Health and Population, Harvard T H Chan School of Public Health, Boston, MA, USA.
| | | | - An Pan
- Department of Epidemiology and Biostatistics, Ministry of Education and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
| | - Craig J McGowan
- Department of Global Health and Population, Harvard T H Chan School of Public Health, Boston, MA, USA
| | - Chelsea Wallace
- School of Population Health, The University of Auckland, Auckland, New Zealand
| | - Fumiaki Imamura
- MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK
| | - Dariush Mozaffarian
- Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA
| | - Boyd Swinburn
- School of Population Health, The University of Auckland, Auckland, New Zealand; Global Obesity Centre, Deakin University, Melbourne, VIC, Australia
| | - Majid Ezzati
- School of Public Health, MRC-PHE Centre for Environment and Health, and WHO Collaborating Centre on NCD Surveillance and Epidemiology, Imperial College London, London, UK
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Bayramiçli M, Şirinoğlu H, Yalçın D. Outcome After Breast Reduction Considering Body Mass Index and Resection Amount. Aesthet Surg J 2017; 37:1103-1110. [PMID: 29044364 DOI: 10.1093/asj/sjx110] [Citation(s) in RCA: 7] [Impact Index Per Article: 0.9] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/13/2022] Open
Abstract
BACKGROUND It is presumed that breast reduction improves patients' quality of life and promotes weight loss. Preoperative body mass index (BMI) and the amount of breast tissue (breast reduction amount [BRA]) in proportion to the patient's body weight are important variables to affect the breast reduction outcome. OBJECTIVE This study was designed to evaluate the short and long-term effects of breast reduction from the perspective of BMI and BRA. METHODS One hundred fifty-seven consecutive patients were invited to participate in the study. All clinical information was recorded on a breast surgery form. Patients completed a standardized questionnaire preoperatively, at postoperative year 1, and after postoperative year 5. Patients were grouped according to their BMI as "normal weight" and "overweight" and according to BRA as "minor/moderate reductions" and "major reductions." The differences in the BMI values and the life scores were compared between the BMI and BRA groups. RESULTS Sixty-four patients were included in the study. Postoperative year 1 BMIs were significantly lower than both the preoperative BMIs and postoperative year 5+ BMIs. The year 1 BMI decrease in the major reduction group was higher than the decrease in the minor/moderate reduction group. The postoperative life scores of all subgroups were better than the preoperative life scores. CONCLUSIONS Reduction mammaplasty has a significant effect on short-term weight loss and the improvement in lifestyle. Patients tend to return to their original body weight in the long term. BRA is a significant variable in short-term weight loss, but neither BMI nor BRA has any other significant effect on the outcome in any time section. LEVEL OF EVIDENCE 4.
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Affiliation(s)
- Mehmet Bayramiçli
- Dr Bayramiçli is a Professor and Dr Yalçın is a Plastic Surgeon, Department of Plastic, Reconstructive, and Aesthetic Surgery, Marmara University School of Medicine, İstanbul, Turkey. Dr Şirinoğlu is a Plastic Surgeon, Department of Plastic, Reconstructive, and Aesthetic Surgery, Dr. Lütfi Kırdar Kartal Training and Research Hospital, İstanbul, Turkey
| | - Hakan Şirinoğlu
- Dr Bayramiçli is a Professor and Dr Yalçın is a Plastic Surgeon, Department of Plastic, Reconstructive, and Aesthetic Surgery, Marmara University School of Medicine, İstanbul, Turkey. Dr Şirinoğlu is a Plastic Surgeon, Department of Plastic, Reconstructive, and Aesthetic Surgery, Dr. Lütfi Kırdar Kartal Training and Research Hospital, İstanbul, Turkey
| | - Doğuş Yalçın
- Dr Bayramiçli is a Professor and Dr Yalçın is a Plastic Surgeon, Department of Plastic, Reconstructive, and Aesthetic Surgery, Marmara University School of Medicine, İstanbul, Turkey. Dr Şirinoğlu is a Plastic Surgeon, Department of Plastic, Reconstructive, and Aesthetic Surgery, Dr. Lütfi Kırdar Kartal Training and Research Hospital, İstanbul, Turkey
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Xiao J, Hua T, Shen H, Zhang M, Wang XJ, Gao YX, Lu Q, Wu C. Associations of metabolic disorder factors with the risk of uncontrolled hypertension: a follow-up cohort in rural China. Sci Rep 2017; 7:743. [PMID: 28389663 PMCID: PMC5429661 DOI: 10.1038/s41598-017-00789-2] [Citation(s) in RCA: 5] [Impact Index Per Article: 0.6] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/11/2016] [Accepted: 03/13/2017] [Indexed: 02/07/2023] Open
Abstract
We evaluated how metabolic disorders affected antihypertension therapy. 2,912 rural Chinese patients with hypertension who provided blood samples, demographic and clinical data at baseline and after 1 year of antihypertension therapy were evaluated. At baseline, 1,515 patients (52.0%) were already receiving drug therapy and 11.4% of them had controlled blood pressure (BP). After 1 year, all 2,912 patients were receiving antihypertension therapy that was administered by community physicians, and 59.42% of them had controlled BP. Central obesity and abnormal triglyceride, high-density lipoprotein cholesterol, and glucose were associated with 15-70% higher risks of uncontrolled hypertension. Metabolic syndrome using the JIS criteria was associated with poor BP control (odds ratio: 1.71 and 1.54 for the baseline and follow-up datasets, respectively). The risk of uncontrolled hypertension increased with the number of metabolic disorders (p for trend <0.01). The presence of ≥3 metabolic disorder factors was associated with higher risks of poor BP control. The associations of metabolic factors and uncontrolled hypertension were stronger for the standard and modified ATP III criteria, compared to the IDF and JIS criteria. Metabolic factors were associated with less effective antihypertension therapy, and all definitions of metabolic syndrome helped identify patients with elevated risks of uncontrolled hypertension.
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Affiliation(s)
- Jing Xiao
- Department of Epidemiology and Medical Statistics, School of Public Health, Nantong University, Nantong, Jiangsu, 226019, P.R. China
| | - Tianqi Hua
- Department of Epidemiology and Medical Statistics, School of Public Health, Nantong University, Nantong, Jiangsu, 226019, P.R. China
| | - Huan Shen
- Department of Epidemiology and Medical Statistics, School of Public Health, Nantong University, Nantong, Jiangsu, 226019, P.R. China
| | - Min Zhang
- Department of Epidemiology and Medical Statistics, School of Public Health, Nantong University, Nantong, Jiangsu, 226019, P.R. China
| | - Xiao-Jian Wang
- Department of Chronic Disease and Prevention, Center for Disease Control and Prevention of Haian, Nantong, Jiangsu, 226600, P.R. China
| | - Yue-Xia Gao
- Department of Epidemiology and Medical Statistics, School of Public Health, Nantong University, Nantong, Jiangsu, 226019, P.R. China.
| | - Qinyun Lu
- Department of Epidemiology and Medical Statistics, School of Public Health, Nantong University, Nantong, Jiangsu, 226019, P.R. China
| | - Chuanli Wu
- Department of Epidemiology and Medical Statistics, School of Public Health, Nantong University, Nantong, Jiangsu, 226019, P.R. China
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Ozen C, Akoglu H, Ozdemirel RO, Omeroglu E, Ozpolat CU, Onur O, Buyuk Y, Denizbasi A. Determination of the chest wall thicknesses and needle thoracostomy success rates at second and fifth intercostal spaces: a cadaver-based study. Am J Emerg Med 2016; 34:2310-2314. [DOI: 10.1016/j.ajem.2016.08.038] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.2] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/01/2016] [Revised: 08/16/2016] [Accepted: 08/16/2016] [Indexed: 11/28/2022] Open
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Esmaeilzadeh S, Cesme F, Oral A, Yaliman A, Sindel D. The utility of dual-energy X-ray absorptiometry, calcaneal quantitative ultrasound, and fracture risk indices (FRAX® and Osteoporosis Risk Assessment Instrument) for the identification of women with distal forearm or hip fractures: A pilot study. Endocr Res 2016; 41:248-60. [PMID: 26864472 DOI: 10.3109/07435800.2015.1120744] [Citation(s) in RCA: 11] [Impact Index Per Article: 1.2] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 11/13/2022]
Abstract
PURPOSE Dual-energy X-ray absorptiometry (DXA) is considered the "gold standard" in predicting osteoporotic fractures. Calcaneal quantitative ultrasound (QUS) variables are also known to predict fractures. Fracture risk assessment tools may also guide us for the detection of individuals at high risk for fractures. The aim of this case-control study was to evaluate the utility of DXA bone mineral density (BMD), calcaneal QUS parameters, FRAX® (Fracture Risk Assessment Tool), and Osteoporosis Risk Assessment Instrument (ORAI) for the discrimination of women with distal forearm or hip fractures. MATERIALS AND METHODS This case-control study included 20 women with a distal forearm fracture and 18 women with a hip fracture as cases and 76 age-matched women served as controls. BMD at the spine, proximal femur, and radius was measured using DXA and acoustic parameters of bone were obtained using a calcaneal QUS device. FRAX® 10-year probability of fracture and ORAI scores were also calculated in all participants. Receiver operating characteristic (ROC) analysis was used to assess fracture discriminatory power of all the tools. RESULTS While all DXA BMD, and QUS variables and FRAX® fracture probabilities demonstrated significant areas under the ROC curves for the discrimination of hip-fractured women and those without, only 33% radius BMD, broadband ultrasound attenuation (BUA), and FRAX® major osteoporotic fracture probability calculated without BMD showed significant discriminatory power for distal forearm fractures. CONCLUSIONS It can be concluded that QUS variables, particularly BUA, and FRAX® major osteoporotic fracture probability without BMD are good candidates for the identification of both hip and distal forearm fractures.
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Affiliation(s)
- Sina Esmaeilzadeh
- a Department of Physical Medicine and Rehabilitation , Istanbul University Istanbul Faculty of Medicine , Istanbul , Turkey
| | - Fatih Cesme
- a Department of Physical Medicine and Rehabilitation , Istanbul University Istanbul Faculty of Medicine , Istanbul , Turkey
| | - Aydan Oral
- a Department of Physical Medicine and Rehabilitation , Istanbul University Istanbul Faculty of Medicine , Istanbul , Turkey
| | - Ayse Yaliman
- a Department of Physical Medicine and Rehabilitation , Istanbul University Istanbul Faculty of Medicine , Istanbul , Turkey
| | - Dilsad Sindel
- a Department of Physical Medicine and Rehabilitation , Istanbul University Istanbul Faculty of Medicine , Istanbul , Turkey
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Basaranoglu M, Najjar SM, Demirbag AE, Senturk H. Significant cohort of non-alcoholic fatty liver disease with portal vein thrombosis in transplant waiting list. World J Hepatol 2016; 8:376-384. [PMID: 26981175 PMCID: PMC4779166 DOI: 10.4254/wjh.v8.i7.376] [Citation(s) in RCA: 4] [Impact Index Per Article: 0.4] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 11/15/2015] [Accepted: 02/24/2016] [Indexed: 02/06/2023] Open
Abstract
AIM: To characterize non-alcoholic fatty liver disease (NAFLD) presentation with esophageal varices.
METHODS: We carried out a retrospective cohort study on 258 patients with esophageal varices at a single tertiary referral center. These patients underwent diagnosis of several liver diseases, including: NAFLD-associated cirrhosis, hepatitis B, hepatitis C, Wilson disease, autoimune liver diseases, and others.
RESULTS: Of the 258 patients, 39% of patients exhibited esophageal varices due to NAFLD-associated cirrhosis. Of the 38 (14.7%) patients developed hepatocellular carcinoma during follow-up, 52% were due to hepatitis B, 26% due to hepatitis C and 13.2% due to NAFLD. Of the 258 patients, 50.0% with NAFLD, 33.3% with hepatitis B, 26.3% with hepatitis C, and 58.3% with other diseases were alive at the end of the 5-year period with a significant difference according to the Kaplan-Meier log Rank test (P = 0.040). Portal vein thrombosis was detected in 47.5% of patients with NAFLD, in 29% of patients with hepatitis B, in 17% of patients with hepatitis C, and in 62% of patients with other related diseases (P < 0.0001).
CONCLUSION: Our study showed a proportionally greater elevation in liver transplant candidacy in patients with NAFLD and portal vein thrombosis. Older patients were more prone to developing cirrhosis, hepatocellular carcinoma and a high mortality rate. However, younger patients exhibited more portal vein thrombosis and gastric varices.
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Heidari-Bakavoli A, Esmaeili H, Hosseini Z, Moohebati M, Azarpazhooh M, Mazidi M, Safarian M, Nematy M, Ferns G, Behrouz M, Ghayour-Mobarhan M. Prevalence of obesity in Iran and its related socio-economic factors. MEDITERRANEAN JOURNAL OF NUTRITION AND METABOLISM 2015. [DOI: 10.3233/mnm-150033] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.2] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/15/2022]
Affiliation(s)
- A.R. Heidari-Bakavoli
- Cardiovascular Research Centre, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
| | - H. Esmaeili
- Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
- Department of Statistics, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
| | - Z. Hosseini
- Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
- Student Research Committee, Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
| | - M. Moohebati
- Cardiovascular Research Centre, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
- Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
| | - M.R. Azarpazhooh
- Cardiovascular Research Centre, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
| | - M. Mazidi
- Institute of Genetics & Developmental Biology, Chinese Academy of Sciences, Beijing, China
| | - M. Safarian
- Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
| | - M. Nematy
- Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
| | - G.A. Ferns
- Division of Medical Education, Brighton & Sussex Medical School, Mayfield House, Falmer, UK
| | - M. Behrouz
- Department of Community Nutrition, School of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute (WHO Collaborating Center), Shahid Beheshti University of Medical Sciences, Tehran, Iran
| | - M. Ghayour-Mobarhan
- Cardiovascular Research Centre, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
- Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
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Bige Ö, Demir A, Saatli B, Koyuncuoğlu M, Saygılı U. Laparoscopy versus laparotomy for the management of endometrial carcinoma in morbidly obese patients: a prospective study. J Turk Ger Gynecol Assoc 2015; 16:164-9. [PMID: 26401110 DOI: 10.5152/jtgga.2015.15128] [Citation(s) in RCA: 15] [Impact Index Per Article: 1.5] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/09/2015] [Accepted: 04/19/2015] [Indexed: 11/22/2022] Open
Abstract
OBJECTIVE To compare the results of total laparoscopic hysterectomy and total abdominal hysterectomy in morbidly obese women with early stage endometrial cancer. MATERIAL AND METHODS This prospective study was conducted on 140 morbidly obese women with body mass indices ≥35 kg/m(2) and presenting with clinical stage 1 endometrial cancer. The patients underwent total laparoscopic hysterectomy (n=70) or total abdominal hysterectomy (n=70), bilateral salpingo-oophorectomy, pelvic lymphadenectomy, and peritoneal washing. Age, parity, menopausal status, weight, height, medical problems, history of previous laparotomy, surgical procedure, operative time, estimated amount of blood loss, preoperative hematocrit, postoperative hematocrit, operative complications, conversion to laparotomy, need for intraoperative or postoperative blood transfusion, intraoperative and postoperative complications, secondary surgery, tumor stage, grade, histology, number of recovered lymph nodes, and visual pain scores of the patients were recorded. RESULTS Postoperative complications were significantly higher in the laparotomy group. Hospital stay in the laparoscopy group was significantly lower than that in the laparotomy group. The visual pain scores were significantly higher in the laparotomy group on the first, second, and third postoperative days and on the day of discharge from the hospital. Resuming activity took a significantly longer time in the laparotomy group (34.70 days) than in the laparoscopic group (17.89 days). CONCLUSION With the availability of skilled endoscopic surgeons, most obese women with early stage endometrial cancer can be safely managed by performing laparoscopy with an excellent surgical outcome, shorter hospitalization, less postoperative pain, and faster resumption of full activity.
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Affiliation(s)
- Özgür Bige
- Department of Obstetrics and Gynecology, Tekirdağ Star Medica Hospital, Tekirdağ, Turkey
| | - Ahmet Demir
- Clinic of Obstetrics and Gynecology, Elazığ Training and Research Hospital, Elazığ, Turkey
| | - Bahadır Saatli
- Department of Obstetrics and Gynecology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
| | - Meral Koyuncuoğlu
- Department of Pathology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
| | - Uğur Saygılı
- Department of Obstetrics and Gynecology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey
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Kilpi F, Webber L, Musaigner A, Aitsi-Selmi A, Marsh T, Rtveladze K, McPherson K, Brown M. Alarming predictions for obesity and non-communicable diseases in the Middle East. Public Health Nutr 2014; 17:1078-86. [PMID: 23642403 PMCID: PMC10282274 DOI: 10.1017/s1368980013000840] [Citation(s) in RCA: 73] [Impact Index Per Article: 6.6] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/13/2012] [Revised: 01/28/2013] [Accepted: 02/05/2013] [Indexed: 11/06/2022]
Abstract
OBJECTIVE The present study aimed to model obesity trends and future obesity-related disease for nine countries in the Middle East; in addition, to explore how hypothetical reductions in population obesity levels could ameliorate anticipated disease burdens. DESIGN A regression analysis of cross-sectional data v. BMI showed age- and sex-specific BMI trends, which fed into a micro simulation with a million Monte Carlo trials for each country. We also examined two alternative scenarios where population BMI was reduced by 1 % and 5 %. SETTING Statistical modelling of obesity trends was carried out in nine Middle East countries (Bahrain, Egypt, Iran, Jordan, Kuwait, Lebanon, Oman, Saudi Arabia and Turkey). SUBJECTS BMI data along with disease incidence, mortality and survival data from national and sub-national data sets were used for the modelling process. RESULTS High rates of overweight and obesity increased in both men and women in most countries. The burden of incident type 2 diabetes, CHD and stroke would be moderated with even small reductions in obesity levels. CONCLUSIONS Obesity is a growing problem in the Middle East which requires government action on the primary prevention of obesity. The present results are important for policy makers to know the effectiveness of obesity interventions on future disease burden.
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Affiliation(s)
- Fanny Kilpi
- National Heart Forum, 7th Floor Victoria House, London WC1B 4AD, UK
| | - Laura Webber
- National Heart Forum, 7th Floor Victoria House, London WC1B 4AD, UK
| | - Abdulrahman Musaigner
- Nutrition and Health Studies Unit, Deanship of Scientific Research, University of Bahrain, Manama, Bahrain
| | - Amina Aitsi-Selmi
- Epidemiology & Public Health, Division of Population Health, University College London, London, UK
| | - Tim Marsh
- National Heart Forum, 7th Floor Victoria House, London WC1B 4AD, UK
| | | | | | - Martin Brown
- National Heart Forum, 7th Floor Victoria House, London WC1B 4AD, UK
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Cong L, Zhan JQ, Yang L, Zhang W, Li SG, Chen C, Zhang HY, Ma ZP, Hao XL, Simayi D, Tao L, Zhao J, Amanguli A, Mohemaiti M, Jing MX, Wang W, Saimaiti A, Zou XG, Gu Y, Li L, Wang YH, Li F, Zhang WJ. Overweight and obesity among low-income Muslim Uyghur women in far western China: correlations of body mass index with blood lipids and implications in preventive public health. PLoS One 2014; 9:e90262. [PMID: 24587304 PMCID: PMC3938656 DOI: 10.1371/journal.pone.0090262] [Citation(s) in RCA: 14] [Impact Index Per Article: 1.3] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/18/2013] [Accepted: 01/03/2014] [Indexed: 11/19/2022] Open
Abstract
BACKGROUND The pandemic of obesity is a global public health concern. Most studies on obesity are skewed toward high-income and urban settings and few covers low-income populations. This study focused on the prevalence of overweight and obesity and their correlations with blood lipids/metabolites/enzymes (bio-indicators) in a rural community typical of low-income in remote western China. METHODS This study was performed in a Muslim ethnic Uyghur rural community in Kashi Prefecture of Xinjiang, about 4,407 km (2,739 miles) away from Beijing. Body mass index (BMI) and major blood bio-indicators (25 total items) were measured and demographic information was collected from 1,733 eligible healthy women aged 21 to 71 yrs, of whom 1,452 had complete data for analysis. More than 92% of the women lived on US$1.00/day or less. According to the Chinese criteria, overweight and obesity were defined as BMI at 24 to <28 kg/m(2) and at ≥ 28 kg/m(2), respectively. RESULTS The average BMI among these low-income women was 24.0 ± 4.0 (95% CI, 17.5-33.7) kg/m(2). The prevalence of obesity and overweight was high at 15.1% and 28.9%, respectively. Among 25 bio-indicators, BMI correlated positively with the levels of 11 bio-indicators including triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TCHOL), glucose (GLU), and uric acid (UA); but negatively with the levels of 5 bio-indicators including high-density lipoprotein cholesterol (HDL-C) and apolipoprotein A/B (APO A/B). CONCLUSIONS This is the first investigation reporting overweight and obesity being common in low-income Muslim Uyghur women, whose BMI correlates with several important blood bio-indicators which are risk factors for diabetes and cardiovascular diseases. These findings may help make preventive public health policies in Uyghur communities. To prevent diabetes and cardiovascular diseases in low-income settings, we therefore propose a cost-effective, two-step strategy first to screen for obesity and then to screen persons with obesity for diabetes and cardiovascular diseases.
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Affiliation(s)
- Li Cong
- Department of Pathology, Shihezi University School of Medicine, Shihezi, Xinjiang, China
- The Key Laboratories for Xinjiang Endemic and Ethnic Diseases, Shihezi University, Shihezi, Xinjiang, China
- Department of Oncology, the First People's Hospital of Suqian, Suqian, Jiangsu, China
| | - Jin Qiong Zhan
- Department of Laboratory Medicine, JiangXi Mental Health Center, Nanchang, Jiangxi, China
| | - Lan Yang
- Department of Pathology, Shihezi University School of Medicine, Shihezi, Xinjiang, China
- The Key Laboratories for Xinjiang Endemic and Ethnic Diseases, Shihezi University, Shihezi, Xinjiang, China
| | - Wei Zhang
- Department of Pathology, Shihezi University School of Medicine, Shihezi, Xinjiang, China
- The Key Laboratories for Xinjiang Endemic and Ethnic Diseases, Shihezi University, Shihezi, Xinjiang, China
| | - Shu Gang Li
- Faculty of Preventive Medicine, Shihezi University School of Medicine, Shihezi, Xinjiang, China
| | - Cheng Chen
- Department of Pathology, Shihezi University School of Medicine, Shihezi, Xinjiang, China
- The Key Laboratories for Xinjiang Endemic and Ethnic Diseases, Shihezi University, Shihezi, Xinjiang, China
| | - Hong Yan Zhang
- Department of Immunization, Xi'an Center for Disease Control and Prevention, Xi'an, Shanxi, China
| | - Zhi Ping Ma
- Department of Pathology, Shihezi University School of Medicine, Shihezi, Xinjiang, China
| | - Xiao Ling Hao
- Department of Pathology, Shihezi University School of Medicine, Shihezi, Xinjiang, China
| | - Dilixia Simayi
- Department of Pathology, Shihezi University School of Medicine, Shihezi, Xinjiang, China
| | - Lin Tao
- Department of Pathology, Shihezi University School of Medicine, Shihezi, Xinjiang, China
| | - Jin Zhao
- Department of Pathology, Shihezi University School of Medicine, Shihezi, Xinjiang, China
| | - A. Amanguli
- Department of Obstetrics and Gynecology, the First Affiliated University Hospital, Shihezi University School of Medicine, Shihezi, Xinjiang, China
| | - Meiliguli Mohemaiti
- Department of Obstetrics and Gynecology, the First Affiliated University Hospital, Shihezi University School of Medicine, Shihezi, Xinjiang, China
| | - Ming Xia Jing
- Faculty of Preventive Medicine, Shihezi University School of Medicine, Shihezi, Xinjiang, China
| | - Wei Wang
- Institute of Humanities, Shihezi University School of Medicine, Shihezi, Xinjiang, China
| | - Abudukeyoumu Saimaiti
- Kashi Prefecture First People's Hospital, Kashi Prefecture Health Bureau, Kashi, Xinjiang, China
| | - Xiao Guang Zou
- Kashi Prefecture First People's Hospital, Kashi Prefecture Health Bureau, Kashi, Xinjiang, China
| | - Yan Gu
- Department of Obstetrics and Gynecology, Institute of Surgery Research, Daping Hospital, the Third Military Medical University, Chongqing, China
| | - Li Li
- Department of Obstetrics and Gynecology, Institute of Surgery Research, Daping Hospital, the Third Military Medical University, Chongqing, China
| | - Ying Hong Wang
- The Key Laboratories for Xinjiang Endemic and Ethnic Diseases, Shihezi University, Shihezi, Xinjiang, China
- Department of Obstetrics and Gynecology, the First Affiliated University Hospital, Shihezi University School of Medicine, Shihezi, Xinjiang, China
| | - Feng Li
- Department of Pathology, Shihezi University School of Medicine, Shihezi, Xinjiang, China
- The Key Laboratories for Xinjiang Endemic and Ethnic Diseases, Shihezi University, Shihezi, Xinjiang, China
| | - Wen Jie Zhang
- Department of Pathology, Shihezi University School of Medicine, Shihezi, Xinjiang, China
- The Key Laboratories for Xinjiang Endemic and Ethnic Diseases, Shihezi University, Shihezi, Xinjiang, China
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Savas E, Öztürk ZA, Tanrıverdi D, Kepekçi Y. Do Ramadan fasting restrictions alter eating behaviours in obese women? JOURNAL OF RELIGION AND HEALTH 2014; 53:135-140. [PMID: 22576675 DOI: 10.1007/s10943-012-9605-x] [Citation(s) in RCA: 12] [Impact Index Per Article: 1.1] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Indexed: 05/31/2023]
Abstract
Ramadan fasting can be considered as a kind of dietary restriction. Eating restriction is a risk factor for later development of eating disorders. The purpose of this study is to evaluate whether Ramadan fasting changes the eating behaviours of obese women. Our sample consisted of 34 obese women who fasted during the Ramadan month. The data were collected by using Questionnaire Form, Eating Attitude Test (EAT) and Bulimic Investigatory Test, Edinburgh (BITE). No statistically significant differences were found between the scores of EAT, BITE, BMI, which were administered within the weeks before and after Ramadan. According to our results, Ramadan fasting restrictions do not seem to change the eating behaviours of obese women.
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Affiliation(s)
- Esen Savas
- Department of Internal Medicine, Faculty of Medicine, Gaziantep University, 27100, Sahinbey, Gaziantep, Turkey
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Ashraf H, Rashidi A, Noshad S, Khalilzadeh O, Esteghamati A. Epidemiology and risk factors of the cardiometabolic syndrome in the Middle East. Expert Rev Cardiovasc Ther 2014; 9:309-20. [DOI: 10.1586/erc.11.9] [Citation(s) in RCA: 10] [Impact Index Per Article: 0.9] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 12/18/2022]
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Basoglu OK, Tasbakan MS. Comparison of clinical characteristics in patients with obesity hypoventilation syndrome and obese obstructive sleep apnea syndrome: a case-control study. CLINICAL RESPIRATORY JOURNAL 2013; 8:167-74. [DOI: 10.1111/crj.12054] [Citation(s) in RCA: 45] [Impact Index Per Article: 3.8] [Reference Citation Analysis] [Track Full Text] [Subscribe] [Scholar Register] [Received: 04/27/2013] [Revised: 08/02/2013] [Accepted: 09/08/2013] [Indexed: 11/29/2022]
Affiliation(s)
- Ozen K. Basoglu
- Department of Chest Diseases; Ege University School of Medicine; Izmir Turkey
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Ozturk S, Baltaci D, Turker Y, Kutlucan A, Yengil E, Deler MH, Gur M, Ankarali H. Effects of the Degree of Obesity on Achieving Target Blood Pressure and Metabolic Deterioration in Obese Individuals: A Population-Based Study. Kidney Blood Press Res 2013; 37:531-9. [DOI: 10.1159/000355733] [Citation(s) in RCA: 3] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 09/23/2013] [Indexed: 11/19/2022] Open
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Çuhadar S, Atay A, Sağlam G, Köseoğlu M, Cuhadar L. Cardiovascular risk factors in young male adults: impact of physical activity and parental education. Cent Asian J Glob Health 2013; 2:44. [PMID: 29755874 PMCID: PMC5927765 DOI: 10.5195/cajgh.2013.44] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/20/2022] Open
Abstract
BACKGROUND This study was conducted to assess whether choices of physical activity, smoking status, and parental education and income were correlated with the health status of young adult males which are important for preventive health policy. METHODS 491 18-29-year old males from lower socioeconomical districts in Turkey participated in this study. Information about demographic characteristics, parental education, household income, smoking status, and physical activity was obtained by means of a standardized questionnaire. BMI and metabolic parameters (serum lipid profile) were assessed. RESULTS Mean total cholesterol, LDL, HDL and triglyceride levels were in the normal range. The physically active group displayed a better lipid profile. No relationship was found between parental education and serum lipids. Smoking was slightly correlated with household income (r=103, p=0.022). CONCLUSION Young adult males who participate in relatively high levels of physical activity are at lower CHD risk than less active ones. The present study also showed that lower socioecnomic status does not always correlate with higher levels of cardiovascular risk factors. In conclusion, data supports that while family history cannot be changed, HDL levels can be modulated by lifestyle factors as in other populations and that with the determined benefits of increasing physical activity and thus, HDL levels, policy reform in schools to promote physical activity are warranted.
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Affiliation(s)
- Serap Çuhadar
- Ataturk Training and Research Hospital, Department of Clinical Biochemistry, Izmir, Turkey
| | - Ayşenur Atay
- Ataturk Training and Research Hospital, Department of Clinical Biochemistry, Izmir, Turkey
| | - Gülcan Sağlam
- Ataturk Training and Research Hospital, Department of Clinical Biochemistry, Izmir, Turkey
| | - Mehmet Köseoğlu
- Ataturk Training and Research Hospital, Department of Clinical Biochemistry, Izmir, Turkey
| | - Levent Cuhadar
- Ataturk Training and Research Hospital, Department of General Surgery, Izmir, Turkey
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Akkoyunlu ME, Altın R, Kart L, Atalay F, Örnek T, Bayram M, Tor M. Investigation of obstructive sleep apnoea syndrome prevalence among long-distance drivers from Zonguldak, Turkey. Multidiscip Respir Med 2013; 8:10. [PMID: 23388467 PMCID: PMC3610186 DOI: 10.1186/2049-6958-8-10] [Citation(s) in RCA: 9] [Impact Index Per Article: 0.8] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/23/2013] [Accepted: 01/23/2013] [Indexed: 11/10/2022] Open
Abstract
BACKGROUND The aim of this study was to assess the prevalence of Obstructive sleep apnoea syndrome (OSAS) in long-distance drivers located in the Zonguldak area and to show the correlation between OSAS and traffic accidents. METHODS In this study, 241 long-distance drivers who were residents of Zonguldak province were interviewed face-to-face and a questionnaire regarding OSAS symptoms, occupational histories, and numbers of accidents was administered. Body mass measurements were also taken from participants. Patients who exhibited evidence of OSAS underwent polysomnography (PSG). RESULTS Snoring was detected in 56% out of all participants, daytime sleepiness was observed in 26.6% and apnoea in 11.6%. All-night PSG was applied to 42 participants who had a high probability of clinical OSAS. Among these, eight had an apnoea-hypopnoea index (AHI) < 5. The prevalence of OSAS was 14.1%. There was a significant relationship between the ratio of traffic accidents per professional years and AHI (r = 0.571; p < 0.005). CONCLUSIONS OSAS prevalence was higher among long-distance drivers in the Zonguldak region. Disease severity was directly proportional to traffic-accident risk, and thus represents a serious social problem.
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Affiliation(s)
- Muhammed E Akkoyunlu
- Chest Department of Pulmonology, Bezmialem Vakif University, Medical Faculty, Fatih, İstanbul, 34093, Turkey
| | - Remzi Altın
- Department of Pulmonology, Karaelmas University, Medical Faculty, Kozlu, Zonguldak, Turkey
| | - Levent Kart
- Chest Department of Pulmonology, Bezmialem Vakif University, Medical Faculty, Fatih, İstanbul, 34093, Turkey
| | - Figen Atalay
- Department of Pulmonology, Karaelmas University, Medical Faculty, Kozlu, Zonguldak, Turkey
| | - Tacettin Örnek
- Department of Pulmonology, Karaelmas University, Medical Faculty, Kozlu, Zonguldak, Turkey
| | - Mehmet Bayram
- Chest Department of Pulmonology, Bezmialem Vakif University, Medical Faculty, Fatih, İstanbul, 34093, Turkey
| | - Meltem Tor
- Department of Pulmonology, Karaelmas University, Medical Faculty, Kozlu, Zonguldak, Turkey
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Alsaffar AA. Validation of a general nutrition knowledge questionnaire in a Turkish student sample. Public Health Nutr 2012; 15:2074-85. [PMID: 22281193 PMCID: PMC10271487 DOI: 10.1017/s1368980011003594] [Citation(s) in RCA: 33] [Impact Index Per Article: 2.5] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/16/2011] [Accepted: 12/08/2011] [Indexed: 01/09/2023]
Abstract
OBJECTIVE To validate the general nutrition knowledge questionnaire developed by Parmenter and Wardle (1999) in a Turkish student sample. DESIGN The original questionnaire of Parmenter and Wardle (1999) was modified and translated into Turkish. The modified questionnaire was administered to second year undergraduate students. Some students completed the questionnaire twice for the measurement of test-retest reliability. Statistical analysis was performed on the responses to measure the internal reliability, test-retest reliability and construct validity. SETTING Students completed the questionnaire under supervision. The questionnaire was completed at the end of lectures. Retest was carried out two weeks after first administration of the test. SUBJECTS A total of 195 undergraduate students studying either nutrition and dietetics (n 90) or engineering (n 105) participated in the study. Of these, 125 students completed the questionnaire on two occasions. RESULTS Overall internal reliability (Cronbach's α = 0·89) and test-retest reliability (0·86) were high. Significant differences between the scores of the two groups of students indicated that the questionnaire had satisfactory construct validity. CONCLUSIONS The modified version of the general nutrition knowledge questionnaire can be used as a tool to examine the nutrition knowledge of adults in Turkey. In the next stage of the study, some adjustments need to be made to the items that led to low reliability values so that these items will be more applicable to the eating habits and patterns of Turkish people.
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Affiliation(s)
- A Aylin Alsaffar
- Department of Nutrition and Dietetics, Yeditepe University, İstanbul, Turkey.
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Sabbağ C. Seasonal BMI changes of rural women living in Anatolia. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH 2012; 9:1159-70. [PMID: 22690188 PMCID: PMC3366605 DOI: 10.3390/ijerph9041159] [Citation(s) in RCA: 8] [Impact Index Per Article: 0.6] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 03/01/2012] [Revised: 03/29/2012] [Accepted: 03/30/2012] [Indexed: 11/21/2022]
Abstract
Today, obesity is one of the most evident public health problems in many parts of the World and it is more common among women. Several factors are affecting women's obesity, among these short term weight fluctuations, either gain or loss, cause severe health disorders, particularly in rural areas where seasonal activity differs significantly throughout the year. Since this case has not been studied in detail, our research focused on prevalence and probable causes of seasonal rural obesity among women in two rural areas of Turkey. The study was undertaken with 100 participants. One-way ANOVA and one-way repeated ANOVA tests were utilized for categorical, continuous and repeated variables as study contains groups with more than one and repeated variables. Overweight is more common in the 18-30 years and 50+ years groups, whereas the absence of obesity, except during winter of 2010 in the 50+ years of age group, is most probably due to the widespread occurrence of diabetes for this age group. The highest BMI values for all groups, which were 25.2 ± 3.39 for 2009 and 26.1 ± 3.40 for 2010, were determined in winter, because of minimum physical activity, while summer BMIs were 24.1 ± 3.39 in 2009 and 25.1 ± 3.35 in 2010. This decrease was most probably due to intense agricultural field work in both regions. The majority of the women claimed that their weight is balanced in summer but results revealed that participants did not lose all the weight which was gained during winter months although BMI showed a significant fall from spring to autumn.
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Affiliation(s)
- Ciğdem Sabbağ
- Food and Beverage Department, Adiyaman University, 02040 Altinsehir, Adiyaman, Turkey.
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Karcaaltincaba D, Buyukkaragoz B, Kandemir O, Yalvac S, Kıykac-Altınbaş S, Haberal A. Gestational diabetes and gestational impaired glucose tolerance in 1653 teenage pregnancies: prevalence, risk factors and pregnancy outcomes. J Pediatr Adolesc Gynecol 2011; 24:62-5. [PMID: 20709580 DOI: 10.1016/j.jpag.2010.07.003] [Citation(s) in RCA: 6] [Impact Index Per Article: 0.4] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/12/2010] [Revised: 07/07/2010] [Accepted: 07/09/2010] [Indexed: 10/19/2022]
Abstract
STUDY OBJECTIVE The aim of this study was to determine the prevalence of gestational diabetes mellitus (GDM) and gestational impaired glucose tolerance (GIGT) in adolescent pregnancies, associated risk factors, and pregnancy complications. DESIGN Retrospective study. SETTINGS Community-based teaching hospital. PARTICIPANTS Results of 1653 pregnant women age ≤ 19 years in 2005-2007 were reviewed. INTERVENTION All pregnant women screened with 50-g glucose challenge test (GCT) and patients with a GCT result ≥ 140 mg/dl underwent a 3-hour 100-g oral glucose tolerance test (OGTT). MAIN OUTCOME MEASURES GDM was diagnosed with at least two abnormal results and GIGT was diagnosed with one abnormal result. GDM and GIGT cases were evaluated for the presence of any associated risk factors and effects of presence of risk factors on pregnancy outcomes. RESULTS The prevalence of GDM was 0.85% (95% CI, 0.41-1.29), GIGT was 0.5% (95% CI, 0.15-0.81) and GDM+GIGT was 1.35% (95% CI, 0.78-1.88) by Carpenter and Coustan criteria. 68% of patients had at least one of the risk factors including body mass index ≥ 25, family history of diabetes and polycystic ovary syndrome (PCOS). Only 9.1% (n = 2) of them required insulin for glucose regulation during pregnancy with 9.1% (n = 2) macrosomia rate. All patients were primiparous and cesarean delivery rate was 27.3% (n = 6). We could not find any effect of presence of risk factors on pregnancy outcomes in GDM and GIGT cases. CONCLUSION We demonstrated that GDM and GIGT are strongly associated with high BMI before pregnancy, PCOS, and family history of diabetes. Since GDM is a state of prediabetes, it is important to diagnose in adolescent pregnancies considering their life expectancy to take preventive measures to avoid diabetes mellitus.
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Affiliation(s)
- Deniz Karcaaltincaba
- Department of Obstetrics and Gynecology, Etlik Zubeyde Hanim Women's Hospital, Gazi University, Ankara, Turkey.
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